Permethrin

(per meth' rin)

P  - Caution when used during pregnancy

L  - Caution when used during lactation

Molecule Info

 

 
Indication & Dosage Topical/Cutaneous
Head pediculosis
Adult: Apply 30-60 ml of 1% lotion (cream rinse) to washed and towel-dried hair and allow to remain for 10 min. Rinse with water. Treatment may be repeated after 7-10 days if lice or nits are detected in hair-scalp junctions.
Topical/Cutaneous
Scabies
Adult: Apply a thin layer of 5% cream into all skin surfaces from the neck to toes. Wash off after 8-14 hr. 30 g of cream is usually sufficient for an average adult.
Topical/Cutaneous
Pediculosis pubis
Adult: Apply sufficient amount of 1% lotion (cream rinse) or 5% cream to thoroughly saturate the pubic area. Allow to remain for 10 min and then rinse with water.
Contraindications Hypersensitivity.
Special Precautions Avoid contact with eyes and mucous membranes. Cross-sensitivity may occur with ragweed or chrysanthemums. History of asthma. Pregnancy and lactation.
Adverse Drug Reactions Mild and transient burning, stinging, pruritus, erythema, tingling, numbness, rash; difficulty in breathing; phototoxic or photosensitisation reactions.
Pregnancy Category (US FDA) Category B: Either animal-reproduction studies have not demonstrated a foetal risk but there are no controlled studies in pregnant women or animal-reproduction studies have shown an adverse effect (other than a decrease in fertility) that was not confirmed in controlled studies in women in the 1sttrimester (and there is no evidence of a risk in later trimesters).
Storage Topical/Cutaneous: Cream: Store at 15-25°C (59-77°F). Lotion (Cream rinse): Store at 15-25°C (59-77°F) or at 20-25°C (68-77°F).
Pharmacology Permethrin is a pyrethroid pediculocide and scabicide. It causes paralysis and death of the pest by inhibiting sodium ion influx through nerve cell membrane channels delaying repolarisation.
Absorption: Small amounts absorbed systemically (topical).
Metabolism: Hepatic via ester hydrolysis; converted to inactive metabolites.
Excretion: Via urine
ATC Classification P03AC04 - permethrin; Belongs to the class of pyrethrines, including synthetic compounds used as ectoparasiticides.

Brand/Product Info


Total Products : 30                              
Brand Name Manufacturer/Marketer Composition Dosage Form Pack Size & Price
AROTRIX Aristopharma Ltd. Permethrin 50mg/gm (5% w/w) cream Cream 15gm & 30gm: 28.00 & 50.00 MRP
DELICE Amico Laboratories Ltd. Permethrin 50mg/gm (5% w/w) cream Cream 15gm & 30gm: 25.00 & 40.00 MRP
DERMANIX Novo Healthcare and Pharma Ltd. Permethrin 50mg/gm (5% w/w) cream Cream 30gm: 40.00 MRP
Elimate Cream Incepta Pharmaceuticals Limited Permethrin BP 50mg/gm Cream 30gm x 1:MRP 40 Tk
ERMITE Jayson Pharmaceuticals Ltd. Permethrin 50mg/gm (5% w/w) cream Cream 30gm: 40.15 IP
FLORIXE Cosmic Chemical Industries Limited Permethrin 50mg/gm (5% w/w) cream Cream 30gm: 40.00 MRP
LICERIN Drug International Ltd Permethrin 50mg/gm (5% w/w) cream Cream 15gm: 25.00 MRP
LORIX Opsonin Pharma Limited Permethrin 50mg/gm (5% w/w) cream Cream 30gm: 40.00 MRP
LOTRIX GlaxoSmithKline Bangladesh Limited Permethrin 50mg/gm (5% w/w) cream Cream 30gm: 55.21 MRP
MITHIN Edruc Limited Permethrin 50mg/gm (5% w/w) cream Cream 15gm & 30gm: 25.00 & 40.00 MRP
NEEPER Kemiko Pharmaceuticals Ltd Permethrin 50mg/gm (5% w/w) cream Cream 15gm & 30gm: 28.00 & 40.00 MRP
NOSCAB Beximco Pharmaceuticals Ltd Permethrin BP 50mg/gm Cream 25gm: 35.00 MRP
PERLS Globe Pharmaceuticals Ltd Permethrin 50mg/gm (5% w/w) cream Cream 30gm: 40.00 MRP
PERMA Alco Pharma Ltd Permethrin 50mg/gm (5% w/w) cream Cream 15gm & 30gm: 24.00 & 35.00 MRP
PERMENIN Medicon Laboratories Ltd Permethrin 50mg/gm (5% w/w) cream Cream 15gm & 30gm: 25.00 & 40.00 MRP
PERMET Gaco Pharmaceutical Ltd. Permethrin 50mg/gm (5% w/w) cream Cream 15gm: 25.00 MRP
PERMETHI Pharmasia Limited Permethrin 50mg/gm (5% w/w) cream Cream 15gm: 25.00 MRP
PERMIN The Acme Laboratories Ltd. Permethrin 50mg/gm (5% w/w) cream Cream 15gm & 30gm: 25.10 & 40.15 MRP
PERMISOL ACI Ltd. Permethrin 50mg/gm (5% w/w) cream Cream 15gm & 30gm: 25.15 & 40.15 MRP
PESIMEX Pharmadesh Laboratories Limited Permethrin 50mg/gm (5% w/w) cream Cream 30gm: 25.09 & 40.15 MRP
REMATHRIN Reman Drug Laboratories Ltd. Permethrin 50mg/gm (5% w/w) cream Cream 15gm & 30gm: 40.50 MRP
SCABEX 15G Square Pharmaceuticals Ltd. Permethrin 5% Cream 15 gm: 30.10 MRP
SCABEX 30G Square Pharmaceuticals Ltd. Permethrin 5% Cream 30 gm: 50.15 MRP
SCABID Chemist Laboratories Ltd. Permethrin 50mg/gm (5% w/w) cream Cream 15gm & 30gm: 28.32 & 40.46 MRP
SCAMETH Millat Pharmaceuticals Ltd Permethrin 50mg/gm (5% w/w) cream Cream 30gm: 40.00 MRP
SCAPER Biopharma Laboratories Ltd Permethrin 50mg/gm (5% w/w) cream Cream 15gm & 30gm: 25.09 & 40.15 MRP
SCARIN IBN SINA Pharmaceutical Industry Ltd. Permethrin 50mg/gm (5% w/w) cream Cream 15gm & 30gm: 30.00 & 45.00 MRP
SKILIN General Pharmaceuticals Ltd Permethrin 50mg/gm (5% w/w) cream Cream 15gm & 30gm: 25.09 & 40.15 MRP
UNIX UniDerma Pharmaceuticals Ltd. Permethrin 50mg/gm (5% w/w) cream Cream 30gm: 40.00 MRP
ZUNEX Rephco Laboratories Ltd. Permethrin 50mg/gm (5% w/w) cream Cream 15gm: 28.00 MRP

Gen. MedInfo

Why is this medication prescribed? 

Permethrin is used to treat scabies ('mites that attach themselves to the skin) in adults and children 2 months of age and older. Over-the-counter permethrin is used to treat lice (small insects that attach themselves to the skin on the head) in adults and children 2 months of age and older. Permethrin is in a class of medications called scabicides and pediculicides. It works by killing lice and mites.

How should this medicine be used?

Permethrin comes as a cream to apply to the skin. Over-the-counter permethrin comes as a lotion to apply to the scalp and hair. Permethrin cream is usually applied to the skin in one treatment, but occasionally a second treatment is necessary. Permethrin lotion is usually applied to the skin in one or two treatments, but occasionally three treatments are necessary. If live mites are seen two weeks (14 days) after the first treatment with permethrin cream, then a second treatment should be applied. If live lice are seen one week after the first treatment with over-the-counter permethrin lotion, then a second treatment should be applied. Follow the directions on your prescription label or the package label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use permethrin exactly as directed. Do not use more or less of it or use it more often than prescribed by your doctor.

Permethrin should only be used on the skin or hair and scalp. Avoid getting permethrin in your eyes, nose, ears, mouth, or vagina. Do not use permethrin on your eyebrows or eyelashes.

If permethrin gets in your eyes, flush them with water right away. If your eyes are still irritated after flushing with water, call your doctor or get medical help right away.

To use permethrin cream, follow these steps:

  1. Apply a thin layer of cream all over your skin from your neck down to your toes (including the soles of your feet). Be careful to apply cream in all skins folds, such as between your toes and fingers or around your waist or buttocks.

  2. For treatment of babies or adults over 65 years of age, the cream should also be applied to the scalp or hairline, temples, and forehead.

  3. You may need to use all of the cream in the tube to cover your body.

  4. Leave the cream on your skin for 8-14 hours.

  5. After 8-14 hours have passed, wash off the cream by bathing or showering.

  6. Your skin may be itchy after treatment with permethrin cream. This does not mean your treatment did not work. If you see live mites 14 days or more after treatment, then you will need to repeat the treatment process.

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To use the lotion, follow these steps:

  1. Wash your hair with shampoo and rinse with water. Do not use a conditioner or a shampoo that contains a conditioner because your treatment will not work as well.

  2. Dry your hair with a towel until just damp.

  3. Shake permethrin lotion well right before use to mix the medication evenly.

  4. Use a towel to cover your face and eyes. Be sure to keep your eyes closed during this treatment. You may need to have an adult help you apply the lotion.

  5. Apply permethrin lotion to your hair and scalp area. Begin to apply the lotion behind your ears and at the back of your neck and then cover all of the hair on your head and scalp.

  6. Keep the lotion on your hair and scalp for 10 minutes after you finish applying permethrin lotion. You should use a timer or clock to track the time.

  7. Rinse your hair and scalp with warm water in a sink. You should not use a shower or bathtub to rinse the lotion away because you do not want to get the lotion over the rest of your body.

  8. Dry your hair with a towel and comb out tangles.

  9. You and anyone who helped you apply the lotion should wash your hands carefully after the application and rinsing steps.

  10. A lice comb may also be used to remove the dead lice and nits (empty egg shells) after this treatment. You may also need to have an adult help you to do this.

  11. If you see live lice on your head 7 days or more after treatment, repeat this entire process.

After using permethrin, sanitize all the clothing, underwear, pajamas, hats, sheets, pillowcases, and towels you have used recently. These items should be washed in very hot water or dry-cleaned. You should also wash combs, brushes, hairs clips and other personal care items in hot water.

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Other uses for this medicine

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
What special precautions should I follow?
 

Before using permethrin, 

  • tell your doctor and pharmacist if you are allergic to permethrin, pyrethrins (A-200, Licide, Pronto, RID), ragweed, any other medications, or any of the ingredients in permethrin cream or lotion. Ask your pharmacist for a list of the ingredients.
  • tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take.
  • tell your doctor if you have or have ever had skin conditions or sensitivities.
  • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while using permethrin, call your doctor.

What special dietary instructions should I follow? 

Unless your doctor tells you otherwise, continue your normal diet.

What side effects can this medication cause?

Permethrin may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • itching of skin or scalp area

  • redness of skin or scalp area

  • numbness or tingling of the skin

  • rash

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Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately:

  • trouble breathing

  • continued irritation of the skin or scalp area

  • infected or pus filled areas of the skin or scalp area

Permethrin may cause other side effects. Call your doctor if you have any unusual problems while using this medication.

What should I know about storage and disposal of this medication?

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

In case of emergency/overdose

In case of overdose, consult your doctor. If the victim has collapsed or is not breathing, consult local medical emergency services.

What other information should I know?

Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your response to this medicine.

Do not let anyone else use your medication. If you still have symptoms and need further treatment, consult your doctor.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Ref:  U.S. National Library of Medicine.


This information is provided for reference only and not a replacement for and should only be used in conjunction with full consultation with a registered medical practitioner. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, mph-bd shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise.

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