mph Bangladesh

Calcipotriol  (US, Calcipotriene)

(kal si poe trye' ol) (kal si poe trye' een)

PCaution when used during lactation  - Caution when used during pregnancy

LCaution when used during lactation  - Caution when used during lactation

Molecule Info

Indication & Dosage Topical/Cutaneous
Mild to moderate plaque psoriasis
Adult: Apply 0.005% cream/ointment once or twice daily. Max: 100 g/wk.
Child: Apply 0.005% cream/ointment 2 times daily. Max: >12 yr: 75 g/wk; 6-12 yr: 50 g/week.
Max Dosage: 
Scalp psoriasis
Adult: 0.005% soln once or twice daily. Max: 60 mL per wk.
Contraindications Hypersensitivity.
Special Precautions Not to be applied on the face; pregnancy and lactation.
Adverse Drug Reactions Skin irritation, erythema, scaling; hypercalcemia w/ high doses.
Pregnancy Category (US FDA) Category C: Either studies in animals have revealed adverse effects on the foetus (teratogenic or embryocidal or other) and there are no controlled studies in women or studies in women and animals are not available. Drugs should be given only if the potential benefit justifies the potential risk to the foetus.
Pharmacology Calcipotriol is a derivative of vitamin D3. It has the property of inducing differentiation and suppression of keratinocytes.
ATC Classification D05AX02 - calcipotriol; Belongs to the class of other topical agents used in the treatment of psoriasis.

Brand/Product Info

Total Products : 4    
Brand Name Manufacturer/Marketer Composition Dosage Form Pack Size & Price
DAIVONEX Leo Pharma/Kapricorn Calcipotriol 50mcg/gm (0.005%) Cream/Ointment 30gm Cream/Ointment: MRP 1377.98 each
DAIVONEX Solution Leo Pharma/Kapricorn Calcipotriol 50mcg/gm (0.005%) Capsule 30ml: 1377.88 MRP
DYVON OINT Square Pharmaceuticals Ltd. Calcipotriol 0.05% Ointment 20 gm: 351.06 MRP
Planex Incepta Pharmaceuticals Limited Calcipotriol BP 0.05mg/gm Ointment 10gm x 1:MRP 200 Tk

Gen. MedInfo

Why is this medication prescribed?

Calcipotriol/Calcipotriene is used to treat psoriasis (a skin disease in which red, scaly patches form due to increased production of skin cells on some areas of the body). Calcipotriol/Calcipotriene is in a class of medications called synthetic vitamin D3 derivatives. It works by slowing the excessive production of skin cells.

How should this medicine be used?

Calcipotriol/Calcipotriene comes as a cream to apply to the skin and as a solution (liquid) to apply to the scalp. The cream and solution are usually applied two times a day. Use Calcipotriol/Calcipotriene at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use Calcipotriol/Calcipotriene exactly as directed. Do not use more or less of it or use it more often than prescribed by your doctor.

Calcipotriol/Calcipotriene controls psoriasis but does not cure it. You may see some improvement in your condition after 2 weeks, but it may take up to 8 weeks before you feel the full benefit of Calcipotriol/Calcipotriene.

Do not apply Calcipotriol/Calcipotriene cream to the face.

Calcipotriol/Calcipotriene solution may catch fire. Do not use this medication near heat or an open flame, such as a cigarette.

To use the cream, follow these steps:

  1. Wash your hands.

  2. Apply a thin layer of cream to the area to be treated. Be careful not to get the cream on your face, especially in or near your eyes.

  3. Rub the cream into the skin until it disappears.

  4. Wash your hands.

To use the solution, follow these steps:

  1. Wash your hands.

  2. Comb hair to remove any unattached psoriasis scales.

  3. Make a part in your hair near the affected areas.

  4. Apply a small amount of the solution to the lesions. Be careful not to get the solution on your forehead or other areas of your face, especially in or near your eyes, nose, or mouth.

  5. Rub the solution into the lesion gently.

  6. Wash your hands.

Other uses for this medicine

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

What special precautions should I follow?

Before using Calcipotriol/Calcipotriene,

  • tell your doctor if you are allergic to Calcipotriol/Calcipotriene, or any other medications.
  • tell your doctor what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
  • tell your doctor if you have or have ever had any medical conditions.
  • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking Calcipotriol/Calcipotriene, call your doctor.
  • plan to avoid unnecessary or prolonged exposure to sunlight and to wear protective clothing (such as a hat), sunglasses, and sunscreen. Calcipotriol/Calcipotriene may make your skin sensitive to sunlight.

What special dietary instructions should I follow?

Unless your doctor tells you otherwise, continue your normal diet.

What should I do if I forget a dose?

Apply the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not apply extra cream or solution to make up for a missed dose.

What side effects can this medication cause?

Calcipotriol/Calcipotriene may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • itching

  • redness

  • worsening of psoriasis

  • burning

  • stinging or tingling of skin

  • dry skin

Some side effects can be serious. If you experience these symptoms, call your doctor immediately:

  • rash

  • irritation of the treated or nearby area of skin

Calcipotriol/Calcipotriene may cause other side effects. Call your doctor if you have any unusual problems while taking this medication or if your symptoms get worse.

What other information should I know?

Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your response to this medicine.

Do not let anyone else use your medication. If you still have symptoms and need further treatment, consult your doctor.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.


This information is provided for reference only and not a replacement for and should only be used in conjunction with full consultation with a registered medical practitioner. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, mph-bd shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise.

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