mph Bangladesh


(dye flor' a sone) 

Molecule Info

Indication & Dosage Topical/Cutaneous
Corticosteroid-responsive dermatoses
Adult: As 0.05% ointment/cream: Apply a thin film over the affected areas 1-4 times daily depending on the severity of the condition.
Special Precautions Substantial systemic absorption may lead to reversible hypothalamic-pituitary-adrenal (HPA) axis suppression, manifestations of Cushing's syndrome, hyperglycaemia and glucosuria. Treatment should be discontinued if there is irritation. Pregnancy and lactation.
Adverse Drug Reactions Burning sensation, itching, redness, dryness. Folliculitis, hypertrichosis, acneiform eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, skin atrophy, striae, miliaria.
Pregnancy Category (US FDA) Category C: Either studies in animals have revealed adverse effects on the foetus (teratogenic or embryocidal or other) and there are no controlled studies in women or studies in women and animals are not available. Drugs should be given only if the potential benefit justifies the potential risk to the foetus.
Storage Topical/Cutaneous: Store at 20-25°C.
Pharmacology Diflorasone diacetate is a corticosteroid that is used topically for its anti-inflammatory, antipruritic and vasoconstrictive actions.
Absorption: Percutaneous absorption is increased when the skin is inflammed or occlusive dressing is used.
Metabolism: Once absorbed systemically, it is metabolised hepatically.
Excretion: Once absorbed systemically, it is excreted renally.
ATC Classification D07AC10 - diflorasone ; Belongs to the class of potent (group III) corticosteroids. Used in the treatment of dermatological diseases.

Brand/Product Info

Total Products : 2  
Brand Name Manufacturer/Marketer Composition Dosage Form Pack Size & Price
ECZENA CRM 0.05% Square Pharmaceuticals Ltd. Diflorasone Diacetate 0.05% Cream 10 gm: 70.48 MRP
ECZENA OINT 0.05% Square Pharmaceuticals Ltd. Diflorasone Diacetate 0.05% Ointment 10 gm: 70.48 MRP

Gen. MedInfo

Why is this medication prescribed?

Diflorasone is used to treat the itching, redness, dryness, crusting, scaling, inflammation (swelling), and discomfort of various skin conditions. Diflorasone is in a class of medications called topical steroids. It works by reducing inflammation and itching.

How should this medicine be used? 

Diflorasone comes as a cream and an ointment to apply to the skin. It is usually applied to the affected area one to three times a day. To help you remember to use diflorasone, apply it around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor to explain any part you do not understand. Use diflorasone exactly as directed. Do not use more or less of it or use it more often than prescribed by your doctor.

Wash or soak the affected area thoroughly before applying the medicine, unless it irritates your skin. Then apply the ointment or cream sparingly in a thin film and rub it in gently.

If you are using diflorasone on your face, keep it out of your eyes.

If you are using diflorasone on a child's diaper area, do not use tight-fitting diapers or plastic pants. Such use may increase side effects.

Do not apply cosmetics or other skin preparations on the treated area without talking with your doctor.

Do not wrap or bandage the treated area unless your doctor tells you to. If your doctor tells you to wrap or bandage the treated area, follow these instructions: 

  1. Soak the area in water or wash it well.

  2. While the skin is moist, gently rub the medication into the affected areas.

  3. Cover the area with plastic wrap (such as Saran Wrap or Handi-Wrap). The plastic may be held in place with a gauze or elastic bandage or adhesive tape on the normal skin beside the treated area. (Instead of using plastic wrap, plastic gloves may be used for the hands, plastic bags for the feet, or a shower cap for the scalp.)

  4. Carefully seal the edges of the plastic to make sure the wrap adheres closely to the skin. If the affected area is moist, you can leave the edges of the plastic wrap partly unsealed or puncture the wrap to allow excess moisture to escape.

  5. Leave the plastic wrapping in place as long as instructed by your doctor. Usually plastic wraps are left in place not more than 12 hours each day.

  6. Cleanse the skin and reapply the medication each time a new plastic wrapping is applied.

Other uses for this medicine

This medication may be prescribed for other uses; ask your doctor for more information.

What special precautions should I follow?

Before using diflorasone,

  • tell your doctor if you are allergic to diflorasone or any other medications.
  • tell your doctor what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking.
  • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while using diflorasone, call your doctor.

What special dietary instructions should I follow? 

Unless your doctor tells you otherwise, continue your normal diet.

What should I do if I forget a dose? 

Apply the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not apply a double dose to make up for a missed one.

What side effects can this medication cause? 

Diflorasone may cause side effects. If you experience any of the following symptoms, call your doctor immediately: 

  • skin burning, itching, or irritation

  • dry skin

  • rash

  • increased hair growth

  • skin discoloration

Long-term use of diflorasone may cause children to grow more slowly. Talk to your doctor about the risks of using this medication.

Diflorasone may cause other side effects. Call your doctor if you have any unusual problems while using this medication.

What other information should I know?

Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your response to this medicine.

Do not let anyone else use your medication. If you still have symptoms and need further treatment, consult your doctor.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Ref:  U.S. National Library of Medicine.

This information is provided for reference only and not a replacement for and should only be used in conjunction with full consultation with a registered medical practitioner. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, mph-bd shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise.

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