Desloratadine

(des lor at' a deen)

PCI / LCI Contraindication for pregnancy & lactation (breast feeding)

Molecule Info

 
Indication & Dosage Oral route
Allergic conditions
Adult: 5 mg once daily.
Child: ≥12 yr: 5 mg once daily; 6-11 yr: 2.5 mg; 1-5 yr: 1.25 mg; 6-11 mth: 1 mg. Doses to be taken once daily. 
Renal impairment: Initially, 5 mg every other day.
Hepatic impairment: Initially, 5 mg every other day.
Administration May be taken with or without food.
Overdosage Treatment is symptomatic and supportive. Standard measures to reduce absorption to be adopted. Haemodialysis unlikely to be useful.
Contraindications Hypersensitivity.
Special Precautions Severe renal or hepatic failure; children <6 mth, elderly, epilepsy, pregnancy and lactation.
Adverse Drug Reactions Headache, fatigue, somnolence, dizziness; nausea, dyspepsia; xerostomia, dysmenorrhoea; pharyngitis.
Pregnancy Category (US FDA) Category C: Either studies in animals have revealed adverse effects on the foetus (teratogenic or embryocidal or other) and there are no controlled studies in women or studies in women and animals are not available. Drugs should be given only if the potential benefit justifies the potential risk to the foetus.
Storage Store below 30°C.
Pharmacology Desloratadine is a long-acting, tricyclic, non-sedating, selective peripheral histamine H1-receptor antagonist which inhibits the release of pro-inflammatory mediators from human mast cells and basophils.
Absorption: Peak plasma concentrations after 3 hr (oral).
Distribution: Protein-binding: 82-87%.
Metabolism: Hepatic; converted to 3-hydroxydesloratadine.
Excretion: Via urine and faeces (as metabolites).
ATC Classification R06AX27 - desloratadine; Belongs to the class of other agents used as systemic antihistamines.

Brand/Product Info


Total Products : 45                                             
Brand Name Manufacturer/Marketer Composition Dosage Form Pack Size & Price
ADLORIN Ad-din pharmaceuticals Ltd. Desloratadine INN 5mg Tablet 100's: 250.00 MRP
ALERTADIN Beacon Pharmaceuticals Limited Desloratadine INN 5mg Tablet 100's: 250.00 MRP
ALORAN Alco Pharma Ltd Desloratadine INN 5mg Tablet 50's: 125.00 MRP
ASLOR Drug International Ltd Desloratadine INN 5mg Tablet 100's: 250.00 MRP
CLAREX Asiatic Laboratories Ltd. Desloratadine INN 5mg Tablet 50's: 125.00 MRP
DEEN Kemiko Pharmaceuticals Ltd Desloratadine INN 5mg Tablet 50's: 125.00 MRP
DELOSIA Pharmasia Limited Desloratadine INN 5mg Tablet 50's: 125.50 MRP
DELOSIA Syrup Pharmasia Limited Desloratadine INN 2.5mg/5ml Syrup 60ml: 25.09 MRP
DELOT Apex Pharmaceuticals Ltd. Desloratadine INN 5mg Tablet 50's: 100.00 MRP
DELOT Syrup Apex Pharmaceuticals Ltd. Desloratadine INN 2.5mg/5ml Syrup 60ml: 25.00 MRP
DERAT Pacific Pharmaceuticals Ltd. Desloratadine INN 5mg Tablet 50's: 125.00 MRP
DES Opsonin Pharma Limited Desloratadine INN 5mg Tablet 50's: 125.00 MRP
DES Syrup Opsonin Pharma Limited Desloratadine INN 2.5mg/5ml Syrup 60ml: 25.00 MRP
DESATROL Navana Pharmaceuticals Limited Desloratadine INN 5mg Tablet 100's: 250.00 MRP
DESATROL Syrup Navana Pharmaceuticals Limited Desloratadine INN 2.5mg/5ml Syrup 60ml: 20.08 MRP
DESLOR Orion Pharma Ltd. Desloratadine INN 5mg Tablet 100's: 251.00 MRP
DESLOR Syrup Orion Pharma Ltd. Desloratadine INN 2.5mg/5ml Syrup 60ml: 25.09 MRP
DESLORIN ACI Ltd. Desloratadine INN 5mg Tablet 100's: 226.00 MRP
DESLORIN Syrup ACI Ltd. Desloratadine INN 2.5mg/5ml Syrup 60ml: 25.09 MRP
DESMARK Hallmark Pharmaceuticals Ltd Desloratadine INN 5mg Tablet 50's: 100.50 MRP
DESMIN Euro Pharma Ltd. Desloratadine INN 5mg Tablet 100's: 250.00 MRP
DESODIN Eskayef Bangladesh Ltd Desloratadine INN 5mg Tablet 50's MRP: 150.00
DESODIN Syrup Eskayef Bangladesh Ltd Desloratadine INN 2.5mg/5ml Syrup 60ml MRP: 25.00
DESTA 5 The White Horse Pharma Desloratadine INN 5mg Tablet 50's: 125.00 MRP
DESTACIN Rangs Pharmaceuticals Ltd. Desloratadine INN 5mg Tablet 50's: 125.00 MRP
DESTIN Unimed & Unihealth Manufacturers Ltd. Desloratadine INN 5mg Tablet 50's: 75.00 MRP
DESTIN Syrup Unimed & Unihealth Manufacturers Ltd. Desloratadine INN 2.5mg/5ml Syrup 60ml: 25.00 MRP
DORA Mystic Pharmaceuticals Limited Desloratadine INN 5mg Tablet 50's: 125.00 MRP
DORA Syrup Mystic Pharmaceuticals Limited Desloratadine INN 2.5mg/5ml Syrup 60ml: 25.75 MRP
LARA Hudson Pharmaceuticals Ltd Desloratadine INN 5mg Tablet 100's: 250.00 MRP
LORADES Novo Healthcare and Pharma Ltd. Desloratadine INN 5mg Tablet 50's: 125.00 MRP
LORADES Syrup Novo Healthcare and Pharma Ltd. Desloratadine INN 2.5mg/5ml Syrup 60ml: 25.00 MRP
MOMENTO Beximco Pharmaceuticals Ltd Desloratadine INN 5mg Tablet 100's: 250.00 MRP
MOMENTO SYRUP Beximco Pharmaceuticals Ltd Desloratadine INN 2.5mg/5ml Syrup 60ml: 25.00 MRP
Neocilor Incepta Pharmaceuticals Limited Desloratadine INN 5 mg Tablet 10x10's:MRP 250 Tk
Neocilor Syrup Incepta Pharmaceuticals Limited Desloratadine INN 2.5mg/5ml Syrup 50ml:MRP 25 Tk
NEOLOR Supreme Pharmaceuticals Ltd. Desloratadine INN 5mg Tablet 50's: 120.00 MRP
ORINEX The Acme Laboratories Ltd. Desloratadine INN 5mg Tablet 100's: 251.00 MRP
PERILOR Bristol Pharma Limited Desloratadine INN 5mg Tablet 100's: 250.00 MRP
REELART Syntho Laboratories Ltd. Desloratadine INN 5mg Tablet 50's: 100.00 MRP
RELERGY General Pharmaceuticals Ltd Desloratadine INN 5mg Tablet 50's: 125.50 MRP
SARINEX Delta Pharma Limited Desloratadine INN 5mg Tablet 50's: 125.00 MRP
SARINEX Syrup Delta Pharma Limited Desloratadine INN 2.5mg/5ml Syrup 60ml: 25.00 MRP
SEDNO 5 Square Pharmaceuticals Ltd. Desloratadine 5mg Tablet 10x10's: 252.00 MRP
SEDNO SYP Square Pharmaceuticals Ltd. Desloratadine 2.5mg/5 ml Syrup 60 ml: 25.17 MRP

Gen. MedInfo

Why is this medication prescribed?

Desloratadine is used to relieve hay fever and allergy symptoms, including sneezing; runny nose; and red, itchy, tearing eyes. It is also used to treat hives. Desloratadine is in a class of medications called antihistamines. It works by blocking histamine, a substance in the body that causes allergic symptoms.

How should this medicine be used?

Desloratadine comes as a tablet, oral solution (liquid), and an orally disintegrating tablet to take by mouth. It is usually taken once a day with or without food. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take desloratadine exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

To take the orally disintegrating tablet, use dry hands to peel back the foil packaging. Immediately take out the tablet and place it on your tongue. The tablet will quickly dissolve and can be swallowed with saliva. Orally disintegrating tablets may be taken with or without water.

Other uses for this medicine

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

What special precautions should I follow?

Before taking desloratadine,

  • tell your doctor if you are allergic to desloratadine, loratadine, or any other medications.
  • tell your doctor what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking.
  • tell your doctor if you have or have ever had kidney or liver disease or phenylketonuria (for orally disintegrating tablets).
  • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking desloratadine, call your doctor.

What special dietary instructions should I follow?

Unless your doctor tells you otherwise, continue your normal diet.

What should I do if I forget a dose?

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

What side effects can this medication cause?

Desloratadine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • headache

  • upset stomach

  • dizziness

  • sore throat

  • dry mouth

  • muscle pain

  • extreme tiredness

  • painful menstruation

 Some side effects can be serious. The following symptom is uncommon, but if you experience it, call your doctor immediately:

  • difficulty breathing

Desloratadine may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

In case of overdose, consult your doctor. If the victim has collapsed or is not breathing, consult local medical emergency services.

What other information should I know?

Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your response to this medicine.

Do not let anyone else use your medication. If you still have symptoms and need further treatment, consult your doctor.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Ref:  U.S. National Library of Medicine.


This information is provided for reference only and not a replacement for and should only be used in conjunction with full consultation with a registered medical practitioner. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, mph-bd shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise.