Cetirizine

(se ti' ra zeen)

PCaution when used during lactation / LCI : Caution - pregnancy; Contraindication - lactation (breast feeding)

Molecule Info

 | See TERMINOLOGY & ABBREVIATIONS |
Indication & Dosage Oral
Allergic conditions
Adult: 10 mg once daily or 5 mg bid.
Child: 6 mth-2 yr: 2.5 mg once daily (up to 2.5 mg bid in children ≥12 mth) ; 2-5 yr: 5 mg once daily or 2.5 mg bid; >6 yr: 10 mg once daily or 5 mg bid. 
Elderly: 
Renal impairment: Half the usual dose. 
Hepatic impairment: Half the usual dose.

Special Populations: Renal impairment: 5 mg once daily.
Administration May be taken with or without food.
Contraindications Hypersensitivity; lactation.
Special Precautions Hepatic or renal impairment; elderly; tasks requiring mental alertness eg, driving or operating heavy machinery; pregnancy.
Adverse Drug Reactions Somnolence, insomnia, malaise, headache, dizziness; GI discomfort, dry mouth, abdominal pain, diarrhoea, nausea, vomiting; occasional hypersensitivity; epistaxis, pharyngitis, bronchospasm.
Drug Interactions Risk of increased INR and epistaxis when taken together with warfarin.
Potentially Fatal: CNS depressants and anticholinergics may potentiate CNS depression of cetirizine. Please consult detailed drug interactions before prescribing.
Pregnancy Category (US FDA) Category B: Either animal-reproduction studies have not demonstrated a foetal risk but there are no controlled studies in pregnant women or animal-reproduction studies have shown an adverse effect (other than a decrease in fertility) that was not confirmed in controlled studies in women in the 1sttrimester (and there is no evidence of a risk in later trimesters).
Storage Oral: Store at 20-25°C. Syr: Can also refrigerate at 2-8°C.
Mechanism of Action Cetirizine is a potent and highly selective antagonist of the peripheral histamine H1-receptor on effector cells in the GI tract, blood vessels and respiratory tract.
Absorption: Absorbed rapidly from the GI tract (oral); peak plasma concentrations after 1 hr. Rate, but not extent, of absorption altered by food.
Distribution: Enters breast milk; crosses the blood-brain barrier (insignificant amounts). Protein-binding: Highly bound.
Excretion: Via the urine (as unchanged); 10 hr (elimination half-life).
ATC Classification R06AE07 - cetirizine ; Belongs to the class of piperazine derivatives used as systemic antihistamines.

Brand/Product Info


Total Products : 105                                                                                                         
Brand Name Manufacturer/Marketer Composition Dosage Form Pack Size & Price
ACITRIN ACI Ltd. Cetirizine dihydrochloride 10mg Tablet 100's: 251.00 MRP
ACITRIN Drop ACI Ltd. Cetirizine dihydrochloride 2.5mg/ml Drop 15ml: 20.00 MRP
ACITRIN Syrup ACI Ltd. Cetirizine dihydrochloride 5mg/5ml Syrup 60ml: 16.06 MRP
ACTIZEN Ambee Pharmaceuticals Ltd. Cetirizine dihydrochloride 10mg Tablet 100's: 203.00 MRP
ACTIZEN Syrup Ambee Pharmaceuticals Ltd. Cetirizine dihydrochloride 5mg/5ml Syrup 60ml: 16.07 MRP
ALAREX Popular Pharmaceuticals Ltd. Cetirizine dihydrochloride 5mg/5ml Syrup 60ml: 16.07 MRP
ALATIN Concord Pharmaceuticals Ltd. Cetirizine dihydrochloride 10mg Tablet 50's: 100.00 MRP
ALATROL Square Pharmaceuticals Ltd. Cetirizine 10mg Tablet 15x10's: 451.50 MRP
ALATROL P-DROP Square Pharmaceuticals Ltd. Cetirizine 2.5mg/ml Paediatric Drops 15 ml: 25.08 MRP
ALATROL SYP Square Pharmaceuticals Ltd. Cetirizine 5mg/5ml Syrup 60 ml: 30.10 MRP
ALETRIN Reman Drug Laboratories Ltd. Cetirizine dihydrochloride 10mg Tablet 100's: 250.00 MRP
ALLERCET Marksman Pharmaceuticals Ltd Cetirizine dihydrochloride 10mg Tablet 100's: 250.00 MRP
ALLERCET Syrup Marksman Pharmaceuticals Ltd Cetirizine dihydrochloride 5mg/5ml Syrup 60ml: 14.80 MRP
ALLERNIL Kemiko Pharmaceuticals Ltd Cetirizine dihydrochloride 10mg Tablet 100's: 250.00 MRP
ALLERNIL Syrup Kemiko Pharmaceuticals Ltd Cetirizine dihydrochloride 5mg/5ml Syrup 60ml: 16.00 MRP
ANTRIN Central Pharmaceuticals Ltd Cetirizine dihydrochloride 10mg Tablet 100's: 250.00 MRP
ARCET NIPRO JMI Pharma Ltd. Cetirizine dihydrochloride 10mg Tablet 100's: 200.00 MRP
ARCET Syrup NIPRO JMI Pharma Ltd. Cetirizine dihydrochloride 5mg/5ml Syrup 60ml: 16.00 MRP
ASITROL Asiatic Laboratories Ltd. Cetirizine dihydrochloride 10mg Tablet 100's: 200.00 MRP
ASITROL Syrup Asiatic Laboratories Ltd. Cetirizine dihydrochloride 5mg/5ml Syrup 60ml: 16.00 MRP
ATRIZIN Beximco Pharmaceuticals Ltd Cetirizine Hydrochloride 10mg Tablet 150's: 375.00 MRP
ATRIZIN DROP Beximco Pharmaceuticals Ltd Cetirizine Hydrochloride BP 2.5mg/ml Drop 15ml: 22.00 MRP
ATRIZIN SYRUP Beximco Pharmaceuticals Ltd Cetirizine Hydrochloride BP 5mg/5ml Syrup 60ml: 20.00 MRP
ATROL Ziska Pharmaceuticals Ltd. Cetirizine dihydrochloride 10mg Tablet 100's: 115.00 MRP
B-CET Belsen Pharmaceuticals Ltd. Cetirizine dihydrochloride 10mg Tablet 100's: 250.00 MRP
B-CET Syrup Belsen Pharmaceuticals Ltd. Cetirizine dihydrochloride 5mg/5ml Syrup 60ml: 16.00 MRP
BPTROL Bristol Pharma Limited Cetirizine dihydrochloride 10mg Tablet 100's: 200.00 MRP
CERITEC S.N. Pharmaceuticals Ltd. Cetirizine dihydrochloride 10mg Tablet 100's: 250.00 MRP
CESIL Silva Pharmaceuticals Limited Cetirizine dihydrochloride 5mg/5ml Syrup 60ml: 16.07 MRP
CETIRIZINE APC Pharmaceuticals Ltd. Cetirizine dihydrochloride 10mg Tablet 100's: 250.00 MRP
CETIRIZINE Syrup APC Pharmaceuticals Ltd. Cetirizine dihydrochloride 5mg/5ml Syrup 60ml: 16.00 MRP
CETIZIN The Acme Laboratories Ltd. Cetirizine dihydrochloride 10mg Tablet 100's: 201.00 MRP
CETJET Reliance Pharmaceuticals Ltd. Cetirizine dihydrochloride 10mg Tablet 100's: 250.00 MRP
CETRA Cosmo Pharma Laboratories Ltd. Cetirizine dihydrochloride 10mg Tablet 100's: 202.00 MRP
CETRIL Chemist Laboratories Ltd. Cetirizine dihydrochloride 10mg Tablet 100's: 252.00 MRP
CETRIL Syrup Chemist Laboratories Ltd. Cetirizine dihydrochloride 5mg/5ml Syrup 60ml: 17.19 MRP
CETRIMAX Novus Pharmaceuticals Ltd. Cetirizine dihydrochloride 10mg Tablet 100's: 250.00 MRP
CETRIN Drug International Ltd Cetirizine dihydrochloride 10mg Tablet 100's: 300.00 MRP
CETZIN Cosmic Chemical Industries Limited Cetirizine dihydrochloride 10mg Tablet 100's: 150.00 MRP
CETZIN Syrup Cosmic Chemical Industries Limited Cetirizine dihydrochloride 5mg/5ml Syrup 60ml: 15.00 MRP
CEZIN Medicon Laboratories Ltd Cetirizine dihydrochloride 10mg Tablet 100's: 250.00 MRP
CEZIN Syrup Medicon Laboratories Ltd Cetirizine dihydrochloride 5mg/5ml Syrup 60ml: 16.00 MRP
CIPZIN Seema Pharmaceuticals Ltd. Cetirizine dihydrochloride 10mg Tablet 100's: 200.00 MRP
CIPZIN Syrup Seema Pharmaceuticals Ltd. Cetirizine dihydrochloride 5mg/5ml Syrup 60ml: 20.00 MRP
CIRIZIN Ad-din pharmaceuticals Ltd. Cetirizine dihydrochloride 10mg Tablet 100's: 171.00 MRP
CIRIZIN Syrup Ad-din pharmaceuticals Ltd. Cetirizine dihydrochloride 5mg/5ml Syrup 60ml: 16.00 MRP
CITIN Opsonin Pharma Limited Cetirizine dihydrochloride 10mg Tablet 100's: 250.00 MRP
CITIN Syrup Opsonin Pharma Limited Cetirizine dihydrochloride 5mg/5ml Syrup 60ml: 16.00 MRP
CITIZEN Zenith Pharmaceuticals Ltd. Cetirizine dihydrochloride 10mg Tablet 100's: 200.00 MRP
CIZIN Nipa Pharmaceuticals Ltd. Cetirizine dihydrochloride 10mg Tablet 100's: 200.00 MRP
CIZIN Syrup Nipa Pharmaceuticals Ltd. Cetirizine dihydrochloride 5mg/5ml Syrup 60ml: 16.00 MRP
CTZ Delta Pharma Limited Cetirizine dihydrochloride 10mg Tablet 100's: 100.00 MRP
DYNO Rephco Laboratories Ltd. Cetirizine dihydrochloride 10mg Tablet 100's: 200.00 MRP
DYZIN Amico Laboratories Ltd. Cetirizine dihydrochloride 10mg Tablet 100's: 125.00 MRP
DYZIN Syrup Amico Laboratories Ltd. Cetirizine dihydrochloride 5mg/5ml Syrup 60ml: 16.00 MRP
ETIZIN Edruc Limited Cetirizine dihydrochloride 10mg Tablet 100's: 252.00 MRP
ETIZIN Syrup Edruc Limited Cetirizine dihydrochloride 5mg/5ml Syrup 60ml: 16.00 MRP
FLUSTAT Decent Pharma Laboratories Ltd. Cetirizine dihydrochloride 10mg Tablet 100's: 200.00 MRP
FLUSTAT Syrup Decent Pharma Laboratories Ltd. Cetirizine dihydrochloride 5mg/5ml Syrup 60ml: 16.00 MRP
HI-TROL Hudson Pharmaceuticals Ltd Cetirizine dihydrochloride 10mg Tablet 100's: 150.00 MRP
HI-TROL Syrup Hudson Pharmaceuticals Ltd Cetirizine dihydrochloride 5mg/5ml Syrup 60ml: 16.00 MRP
HISTACET Medimet Pharmaceuticals Ltd Cetirizine dihydrochloride 10mg Tablet 100's: 200.00 MRP
HISTACET Syrup Medimet Pharmaceuticals Ltd Cetirizine dihydrochloride 5mg/5ml Syrup 60ml: 15.50 MRP
I-CET Indo-Bangla Pharmaceuticals Works Ltd. Cetirizine dihydrochloride 10mg Tablet 100's: 250.00 MRP
I-CET Syrup Indo-Bangla Pharmaceuticals Works Ltd. Cetirizine dihydrochloride 5mg/5ml Syrup 60ml: 16.00 MRP
MOSET Monico Pharma Limited Cetirizine dihydrochloride 10mg Tablet 50's: 125.00 MRP
MOSET Syrup Monico Pharma Limited Cetirizine dihydrochloride 5mg/5ml Syrup 60ml: 16.00 MRP
MYSTACIN Mystic Pharmaceuticals Limited Cetirizine dihydrochloride 5mg/5ml Syrup 60ml: 16.00 MRP
NOLER Alco Pharma Ltd Cetirizine dihydrochloride 10mg Tablet 50's: 125.00 MRP
NOLER Syrup Alco Pharma Ltd Cetirizine dihydrochloride 5mg/5ml Syrup 60ml: 16.00 MRP
NOSEMIN IBN SINA Pharmaceutical Industry Ltd. Cetirizine dihydrochloride 10mg Tablet 100's: 300.00 MRP
NOSEMIN Syrup IBN SINA Pharmaceutical Industry Ltd. Cetirizine dihydrochloride 5mg/5ml Syrup 60ml: 20.00 MRP
NOTROL Aexim Pharmaceutical Ltd. Cetirizine dihydrochloride 10mg Tablet 100's: 150.00 MRP
ONTIN Eskayef Bangladesh Ltd Cetirizine Hydrochloride 10mg Tablet 100's MRP: 250.00
ONTIN Syrup Eskayef Bangladesh Ltd Cetirizine Hydrochloride BP 5mg/5ml Syrup 60ml MRP: 16.00
OPZIN Pharmadesh Laboratories Limited Cetirizine dihydrochloride 10mg Tablet 100's: 150.00 MRP
OPZIN Syrup Pharmadesh Laboratories Limited Cetirizine dihydrochloride 5mg/5ml Syrup 60ml: 15.00 MRP
ORGY Kumudini Pharma Ltd Cetirizine dihydrochloride 10mg Tablet 100's: 250.00 MRP
ORGY Syrup Kumudini Pharma Ltd Cetirizine dihydrochloride 5mg/5ml Syrup 60ml: 20.00 MRP
PROCET Somatec Pharmaceuticals Ltd. Cetirizine dihydrochloride 10mg Tablet 100's: 201.00 MRP
PROCET Syrup Somatec Pharmaceuticals Ltd. Cetirizine dihydrochloride 5mg/5ml Syrup 60ml: 16.06 MRP
PROLER Hallmark Pharmaceuticals Ltd Cetirizine dihydrochloride 10mg Tablet 50's: 125.00 MRP
PROLER Syrup Hallmark Pharmaceuticals Ltd Cetirizine dihydrochloride 5mg/5ml Syrup 60ml: 16.07 MRP
RHINIL Aristopharma Ltd. Cetirizine dihydrochloride 10mg Tablet 100's: 250.00 MRP
RHINIL Syrup Aristopharma Ltd. Cetirizine dihydrochloride 5mg/5ml Syrup 60ml: 17.00 MRP
RIZ Orion Pharma Ltd. Cetirizine dihydrochloride 10mg Tablet 100's: 251.00 MRP
RIZ Syrup Orion Pharma Ltd. Cetirizine dihydrochloride 5mg/5ml Syrup 60ml: 16.06 MRP
RIZIN Gaco Pharmaceutical Ltd. Cetirizine dihydrochloride 10mg Tablet 50's: 125.00 MRP
RIZIN Syrup Gaco Pharmaceutical Ltd. Cetirizine dihydrochloride 5mg/5ml Syrup 60ml: 16.00 MRP
SARCET 10 The White Horse Pharma Cetirizine dihydrochloride 10mg Tablet 100's: 250.00 MRP
SARTEC Rangs Pharmaceuticals Ltd. Cetirizine dihydrochloride 10mg Tablet 100's: 100.00 MRP
SARTEC Syrup Rangs Pharmaceuticals Ltd. Cetirizine dihydrochloride 5mg/5ml Syrup 60ml: 16.00 MRP
SATROL Shamsul Alamin Pharmaceuticals Ltd Cetirizine dihydrochloride 10mg Tablet 100's: 150.00 MRP
SYTROL Syntho Laboratories Ltd. Cetirizine dihydrochloride 10mg Tablet 100's: 250.00 MRP
SYTROL Syrup Syntho Laboratories Ltd. Cetirizine dihydrochloride 5mg/5ml Syrup 60ml: 16.00 MRP
TIRAMINE Renata Limited Cetirizine dihydrochloride 10mg Tablet 100's: 254.00 MRP
TIZ Euro Pharma Ltd. Cetirizine dihydrochloride 10mg Tablet 100's: 275.00 MRP
TIZ Syrup Euro Pharma Ltd. Cetirizine dihydrochloride 5mg/5ml Syrup 60ml: 16.00 MRP
TRIN Globe Pharmaceuticals Ltd Cetirizine dihydrochloride 10mg Tablet 100's: 250.00 MRP
TRIN Syrup Globe Pharmaceuticals Ltd Cetirizine dihydrochloride 5mg/5ml Syrup 60ml: 15.00 MRP
TRIZLN Navana Pharmaceuticals Limited Cetirizine dihydrochloride 10mg Tablet 100's: 251.00 MRP
TRIZLN Syrup Navana Pharmaceuticals Limited Cetirizine dihydrochloride 5mg/5ml Syrup 60ml: 16.06 MRP
ZINAL Unimed & Unihealth Manufacturers Ltd. Cetirizine dihydrochloride 10mg Tablet 50's: 125.00 MRP
ZINAL Syrup Unimed & Unihealth Manufacturers Ltd. Cetirizine dihydrochloride 15mg/5ml Syrup 60ml, 100ml: 20.00 & 16.00 MRP
ZYRTEC Desh Pharmaceuticals (Pvt) Ltd Cetirizine dihydrochloride 10mg Tablet 100's: 250.00 MRP

Gen. MedInfo

Why is this medication prescribed?

Cetirizine is used to temporarily relieve the symptoms of hay fever (allergy to pollen, dust, or other substances in the air) and allergy to other substances (such as dust mites, animal dander, cockroaches, and molds). These symptoms include sneezing; runny nose; itchy, red, watery eyes; and itchy nose or throat. Cetirizine is also used to treat itching and redness caused by hives. However, cetirizine does not prevent hives or other allergic skin reactions. Cetirizine is in a class of medications called antihistamines. It works by blocking the action of histamine, a substance in the body that causes allergic symptoms.

Cetirizine is also available in combination with pseudoephedrine (Sudafed, others). This monograph only includes information about the use of cetirizine alone. If you are taking the cetirizine and pseudoephedrine combination product, read the information on the package label or ask your doctor for more information.

How should this medicine be used?

Cetirizine may come as a tablet, a chewable tablet, an extended release tablet or a syrup (liquid) to take by mouth. It is usually taken once a day with or without food. Take cetirizine at around the same time every day. Follow the directions on your package label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take cetirizine exactly as directed. Do not take more or less of it or take it more often than directed on the package label or as recommended by your doctor.

Do not use cetirizine to treat hives that are bruised or blistered, that are an unusual color, or that do not itch. Call your doctor if you have these types of hives.

Stop taking cetirizine and call your doctor if your hives do not improve during the first 3 days of your treatment or if your hives last longer than 6 weeks. If you do not know the cause of your hives, call your doctor.

If you are taking cetirizine to treat hives, and you develop any of the following symptoms, get emergency medical help right away: difficulty swallowing, speaking, or breathing; swelling in and around the mouth or swelling of the tongue; wheezing; drooling; dizziness; or loss of consciousness. These may be symptoms of a life-threatening allergic reaction called anaphylaxis. If your doctor suspects that you may experience anaphylaxis with your hives, he may prescribe an epinephrine injector. Do not use cetirizine in place of the epinephrine injector.

Other uses for this medicine

This medication may be prescribed for other uses; ask your doctor for more information.

What special precautions should I follow?

Before taking cetirizine,

  • tell your doctor if you are allergic to cetirizine, hydroxyzine or any other medications.
  • tell your doctor what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: antidepressants, medications for anxiety, medications for mental illness, medications for seizures, other medications for cold and allergy, sedatives, sleeping pills, tranquilizers, and theophylline (Theo-24, Theolair). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
  • tell your doctor if you have or have ever had kidney or liver disease.
  • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking cetirizine, call your doctor.
  • you should know that cetirizine may make you drowsy. Do not drive a car or operate machinery until you know how this medication affects you.
  • remember that alcohol can add to the drowsiness caused by this medication. Avoid drinking alcoholic beverages while taking this medication.

What special dietary instructions should I follow?

Unless your doctor tells you otherwise, continue your normal diet.

What should I do if I forget a dose?

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

What side effects can this medication cause?

Cetirizine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • drowsiness

  • excessive tiredness

  • dry mouth

  • stomach pain

  • diarrhea

  • vomiting

Some side effects can be serious. The following symptom is uncommon, but if you experience it, call your doctor immediately:

  • difficulty breathing or swallowing

Cetirizine may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

What should I know about storage and disposal of this medication?

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

In case of emergency/overdose

In case of overdose, consult your doctor. If the victim has collapsed or is not breathing, consult local medical emergency services.

Symptoms of overdose may include:

  • restlessness

  • irritability

  • drowsiness

This medication may cause other side effects.  Consult your doctor if you have any unusual problems while taking this.

What other information should I know?

Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your response to this medicine.

Do not let anyone else use your medication. If you still have symptoms and need further treatment, consult your doctor.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Ref:  U.S. National Library of Medicine.


This information is provided for reference only and not a replacement for and should only be used in conjunction with full consultation with a registered medical practitioner. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, mph-bd shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise.