mph Bangladesh


Cefpodoxime

(sef pode ox' eem)

PCaution when used during lactation : Caution when used during pregnancy

LCaution when used during lactation : Caution when used during lactation

Molecule Info

 | See TERMINOLOGY & ABBREVIATIONS |
Indication(s) & Dosage Respiratory tract infections
Adult: 100-200 mg every 12 hr.
Child: 8-10 mg/kg/day in 2 divided doses. Max dose: 400 mg daily. 

Urinary tract infections
Adult: 100-200 mg every 12 hr.
Child: 8-10 mg/kg/day in 2 divided doses. Max dose: 400 mg daily. 

Skin infections
Adult: 200-400 mg every 12 hr.
Child: 8-10 mg/kg/day in 2 divided doses. Max dose: 400 mg/day.

Otitis media
Child: 8-10 mg/kg/day in 2 divided doses. Max dose: 400 mg daily. 


Uncomplicated gonorrhoea
Adult: A single dose of 200 mg may be used. 
Renal impairment: Dose reduction may be required. Dose should be given after each dialysis session for patients on haemodialysis.

CrCl (ml/min) Dosage Recommendation
10-39 Increase dosing intervals to 24 hrly.
<10 Increase dosing intervals to 48 hrly.

Special Populations: Increase dosing intervals in patients with severe renal impairment or CrCl <40 mL/min.

Administration Should be taken with food. Take after meals.
Overdosage Toxic symptoms may include nausea, vomiting, epigastric distress and diarrhoea. Haemodialysis or peritoneal dialysis may aid in the removal of cefpodoxime from the body, particularly if renal function is compromised.
Contraindications Hypersensitivity.
Special Precautions History of allergy to penicillin; severe renal impairment; pregnancy and lactation.
Adverse Drug Reaction(s) Anaphylactic shock; purpuric nephritis, skin rash, pruritus; diarrhoea, nausea, abdominal pain, vomiting.
Potentially Fatal: Pseudomembranous colitis; nephrotoxicity.
Drug Interactions Antacids or H2-blockers may decrease the absorption of cefpodoxime. Probenecid inhibits renal excretion.
Potentially Fatal: Monitor renal function during admin. Additive nephrotoxic effects with furosemide. Please consult detailed drug interactions before prescribing.
Food Interaction Food delays absorption; cefpodoxime levels may be increased with food.
Lab Interference Urinary glucose test by Benedict's and Fehling's tests solution may produce false-positive result. May induce a positive direct Coombs' test.
Pregnancy Category (FDA) Category B: Either animal-reproduction studies have not demonstrated a foetal risk but there are no controlled studies in pregnant women or animal-reproduction studies have shown an adverse effect (other than a decrease in fertility) that was not confirmed in controlled studies in women in the 1sttrimester (and there is no evidence of a risk in later trimesters).
Storage Oral: Store at 20-25°C.
Pharmacology Cefpodoxime binds to one or more of the penicillin-binding proteins (PBPs) which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell wall, thus inhibiting biosynthesis and arresting cell wall assembly resulting in bacterial cell death.
Absorption: Decreased absorption in conditions of low gastric acidity. Bioavailability: about 50%.
Distribution: Respiratory and GU tract (therapeutic concentrations); enters breast milk (low concentrations). Protein-binding: 20-30%.
Metabolism: De-esterified to cefpodoxime in the intestinal lumen.
Excretion: Via the urine (as unchanged); removed by dialysis; 2-3 hr (elimination half-life); prolonged in renal impariment.
ATC Classification J01DD13 - cefpodoxime

Brand/Product Info


Total Products : 104                                                                                                        
Brand Name Manufacturer/Marketer Composition Dosage Form Pack Size & Price
CEDOFAX The White Horse Pharma Cefpodoxime proxetil USP 100mg & 200mg Capsule 100mg x12's, 200mg x6's: 264.00 & 320.00 MRP
CEFDOX ACI Ltd. Cefpodoxime proxetil INN 40mg/5ml Suspension 50ml: 98.37 MRP
CEFIPOD Asiatic Laboratories Ltd. Cefpodoxime proxetil INN 20mg/ml Drop 15ml: 60.00 MRP
CEFIPOD Capsule Asiatic Laboratories Ltd. Cefpodoxime proxetil INN 100mg & 200mg Capsule 100mg x8's, 200mg x6's: 112.00 & 150.00 MRP
CEFIPOD DS Asiatic Laboratories Ltd. Cefpodoxime proxetil INN 80mg/5ml Suspension 50ml: 175.00 MRP
CEFIPOD Suspension Asiatic Laboratories Ltd. Cefpodoxime proxetil INN 40mg/5ml Suspension 50ml: 98.00 MRP
CEFOBID Unimed & Unihealth Manufacturers Ltd. Cefpodoxime proxetil INN 40mg/5ml Suspension 50ml: 98.00 MRP
CEFODIM Pacific Pharmaceuticals Ltd. Cefpodoxime proxetil INN 100mg & 200mg Capsule 100mg x20's, 200mg x10's: 440.00 & 400.00 MRP
CEFODIM Suspension Pacific Pharmaceuticals Ltd. Cefpodoxime proxetil INN 40mg/5ml Suspension 50ml: 80.00 MRP
CEFODOX Bristol Pharma Limited Cefpodoxime proxetil INN 100mg Capsule 100mg x4's: 88.00 MRP
CEFODOX Suspension Bristol Pharma Limited Cefpodoxime proxetil INN 40mg/5ml Suspension 50ml: 95.00 MRP
CEFOMIN Popular Pharmaceuticals Ltd. Cefpodoxime proxetil INN 100mg & 200mg Capsule 10's each: 200.80 & 381.40 MRP
CEFOMIN Suspension Popular Pharmaceuticals Ltd. Cefpodoxime proxetil INN 40mg/5ml Suspension 50ml: 96.36 MRP
CEFORAN Drug International Ltd Cefpodoxime proxetil INN 100mg & 200mg Capsule 16's each: 192.00 & 400.00 MRP
CEFORAN DS Drug International Ltd Cefpodoxime proxetil INN 80mg/5ml Suspension 50ml: 175.00 MRP
CEFORAN Suspension Drug International Ltd Cefpodoxime proxetil INN 40mg/5ml Suspension 50ml, 100ml: 75.00 & 120.00 MRP
CEPDOXIM Alco Pharma Ltd Cefpodoxime proxetil INN 100mg & 200mg Capsule 16's each: 320.00 & 480.00 MRP
CEPDOXIM Suspension Alco Pharma Ltd Cefpodoxime proxetil INN 40mg/5ml Suspension 50ml, 100ml: 90.00 & 175.00 MRP
CEPOXID Apex Pharmaceuticals Ltd. Cefpodoxime proxetil INN 40mg/5ml Suspension 50ml: 98.00 MRP
CP The Acme Laboratories Ltd. Cefpodoxime proxetil INN 200mg Tablet 8's: 337.28 MRP
CP Drop The Acme Laboratories Ltd. Cefpodoxime proxetil INN 20mg/ml Drop 15ml: 60.22 MRP
CP Suspension The Acme Laboratories Ltd. Cefpodoxime proxetil INN 40mg/5ml Suspension 50ml: 98.36 MRP
DESBAC General Pharmaceuticals Ltd Cefpodoxime proxetil INN 100mg Capsule 12's: 264.72 MRP
DESBAC Suspension General Pharmaceuticals Ltd Cefpodoxime proxetil INN 40mg/5ml Suspension 50ml: 98.37 MRP
DOFIXIM IBN SINA Pharmaceutical Industry Ltd. Cefpodoxime proxetil INN 200mg Tablet 12's: 480.00 MRP
DOFIXIM Capsule IBN SINA Pharmaceutical Industry Ltd. Cefpodoxime proxetil INN 100mg Capsule 8's: 168.00 IP
DOFIXIM Suspension IBN SINA Pharmaceutical Industry Ltd. Cefpodoxime proxetil INN 40mg/5ml Suspension 50ml: 100.00 IP
DxPROXIL Monico Pharma Limited Cefpodoxime proxetil INN 40mg/5ml Suspension 50ml: 98.00 MRP
E-POD Edruc Limited Cefpodoxime proxetil INN 100mg Capsule 12's: 480.00 IP
E-POD Suspension Edruc Limited Cefpodoxime proxetil INN 40mg/5ml Suspension 50ml: 96.00 IP
EPOXIM Peoples Pharma Ltd. Cefpodoxime proxetil INN 100mg & 200mg Capsule 100mg x12's, 200mg x8's: 211.02 & 246.19 MRP
EPOXIM Suspension Peoples Pharma Ltd. Cefpodoxime proxetil INN 40mg/5ml Suspension 50ml, 100ml: 86.16 & 158.27 MRP
EVEDOXIM Everest Pharmaceuticals Ltd. Cefpodoxime proxetil INN 20mg/ml Drop 15ml: 60.00 MRP
EVEDOXIM Capsule Everest Pharmaceuticals Ltd. Cefpodoxime proxetil INN 100mg Capsule 12's: 264.00 MRP
EVEDOXIM Suspension Everest Pharmaceuticals Ltd. Cefpodoxime proxetil INN 40mg/5ml Suspension 50ml: 85.00 MRP
INSTINA Ziska Pharmaceuticals Ltd. Cefpodoxime proxetil INN 40mg/5ml Suspension 50ml: 98.00 MRP
KIDCEF Beacon Pharmaceuticals Limited Cefpodoxime proxetil INN 50mg/5ml Suspension 50ml: 98.00 MRP
METOXIM Sandoz/Novartis Cefpodoxime proxetil INN 100mg & 200mg Tablet 100mg x 14's: MRP 350.00; 200mg x 14's: MRP 630.00
METOXIM SUSPENSION Sandoz/Novartis Cefpodoxime proxetil INN 40mg/5ml Suspension 50ml: MRP 100.00
NEOPROX Somatec Pharmaceuticals Ltd. Cefpodoxime proxetil INN 20mg/ml Drop 15ml: 60.23 MRP
NEOPROX Capsule Somatec Pharmaceuticals Ltd. Cefpodoxime proxetil INN 200mg Capsule 8's: 321.20 MRP
NEOPROX DS Somatec Pharmaceuticals Ltd. Cefpodoxime proxetil INN 80mg/5ml Suspension 50ml: 175.66 MRP
NEOPROX Suspension Somatec Pharmaceuticals Ltd. Cefpodoxime proxetil INN 40mg/5ml Suspension 50ml: 98.37 MRP
PEDICEF Orion Pharma Ltd. Cefpodoxime proxetil INN 20mg/ml Drop 15ml: 60.23 MRP
PEDICEF DS Orion Pharma Ltd. Cefpodoxime proxetil INN 80mg/5ml Suspension 50ml: 175.66 MRP
PEDICEF Suspension Orion Pharma Ltd. Cefpodoxime proxetil INN 40mg/5ml Suspension 50ml: 98.37 MRP
PODO Kemiko Pharmaceuticals Ltd Cefpodoxime proxetil INN 40mg/5ml Suspension 50ml, 100ml: 98.00 & 190.00 MRP
PODO 100 Kemiko Pharmaceuticals Ltd Cefpodoxime proxetil INN 100mg Tablet 10's: 220.00 MRP
PODOXI Chemist Laboratories Ltd. Cefpodoxime proxetil INN 100mg Capsule 8's: 160.00 MRP
PODOXI Suspension Chemist Laboratories Ltd. Cefpodoxime proxetil INN 40mg/5ml Suspension 50ml: 90.00 MRP
PROCTIL Medicon Laboratories Ltd Cefpodoxime proxetil INN 40mg/5ml Suspension 50ml: 98.00 MRP
ROVANTIN Opsonin Pharma Limited Cefpodoxime proxetil INN 100mg & 200mg Tablet 10's each: 140.00 & 250.00 MRP
ROVANTIN Drop Opsonin Pharma Limited Cefpodoxime proxetil INN 20mg/ml Drop 15ml: 60.00 MRP
ROVANTIN DS Opsonin Pharma Limited Cefpodoxime proxetil INN 80mg/5ml Suspension 50ml: 175.00 MRP
ROVANTIN Suspension Opsonin Pharma Limited Cefpodoxime proxetil INN 40mg/5ml Suspension 50ml: 98.00 MRP
ROXETIL 100 Healthcare Pharmacuticals Ltd. Cefpodoxime Proxetil USP equivalent to Cefpodoxime 100 mg Capsule 16's MRP 352 Tk
ROXETIL 200 Healthcare Pharmacuticals Ltd. Cefpodoxime Proxetil USP equivalent to Cefpodoxime 200mg Capsule 12's MRP 504 Tk
ROXETIL D/S Healthcare Pharmacuticals Ltd. Cefpodoxime Proxetil USP equivalent to Cefpodoxime 80mg/5ml Suspension 50ml, MRP 95 Tk
SARELOX Sanofi Cefpodoxime proxetil INN 100mg & 200mg Tablet 12's each: 264.96 & 505.92 MRP
SARELOX Drop Sanofi Cefpodoxime proxetil INN 20mg/ml Drop 15ml: 60.23 MRP
SARELOX DS Sanofi Cefpodoxime proxetil INN 80mg/5ml Suspension 50ml: 175.66 MRP
SARELOX Suspension Sanofi Cefpodoxime proxetil INN 40mg/5ml Suspension 50ml: 98.37 MRP
SEFOX Navana Pharmaceuticals Limited Cefpodoxime proxetil INN 100mg Capsule 12's: 264.96 MRP
SEFOX Suspension Navana Pharmaceuticals Limited Cefpodoxime proxetil INN 40mg/5ml Suspension 50ml: 95.35 MRP
STARIN Eskayef Bangladesh Ltd Cefpodoxime Proxetil USP equivalent to Cefpodoxime 100mg Capsule 100mg x16's MRP: 352.00
STARIN Drop Eskayef Bangladesh Ltd Cefpodoxime Proxetil USP equivalent to Cefpodoxime 20mg/ml Drop 15ml MRP: 60.00
STARIN DS Eskayef Bangladesh Ltd Cefpodoxime Proxetil USP equivalent to Cefpodoxime 80mg/5ml Suspension 50ml MRP: 150.00
STARIN Suspension Eskayef Bangladesh Ltd Cefpodoxime proxetil INN 40mg/5ml Suspension 50ml MRP: 98.00
SUDOXIM S.N. Pharmaceuticals Ltd. Cefpodoxime proxetil INN 40mg/5ml Suspension 50ml: 95.36 MRP
TAXETIL Aristopharma Ltd. Cefpodoxime proxetil INN 20mg/ml Drop 15ml: 62.00 MRP
TAXETIL Capsule Aristopharma Ltd. Cefpodoxime proxetil INN 100mg & 200mg Capsule 100mg x18's, 200mg x8's: 396.00 & 320.00 MRP
TAXETIL DS Aristopharma Ltd. Cefpodoxime proxetil INN 80mg/5ml Suspension 50ml: 175.00 MRP
TAXETIL Suspension Aristopharma Ltd. Cefpodoxime proxetil INN 40mg/5ml Suspension 50ml, 100ml: 99.00 & 195.00 MRP
TORAXIM Delta Pharma Limited Cefpodoxime proxetil INN 20mg/ml Drop 15ml: 60.00 MRP
TORAXIM Suspension Delta Pharma Limited Cefpodoxime proxetil INN 40mg/5ml Suspension 50ml: 98.00 MRP
TRUCEF Renata Limited Cefpodoxime proxetil INN 100mg & 200mg Tablet 10's each: 220.80 & 421.60 MRP
TRUCEF Drop Renata Limited Cefpodoxime proxetil INN 20mg/ml Drop 15ml: 60.23 MRP
TRUCEF DS Renata Limited Cefpodoxime proxetil INN 80mg/5ml Suspension 50ml: 175.66 MRP
TRUCEF Suspension Renata Limited Cefpodoxime proxetil INN 40mg/5ml Suspension 50ml,100ml: 98.37 & 190.72 MRP
VANPROX 100 Square Pharmaceuticals Ltd. Cefpodoxime 100mg Capsule 2x6's: 265.68 MRP
VANPROX 200 Square Pharmaceuticals Ltd. Cefpodoxime 200mg Capsule 1x6's: 253.74 MRP
VANPROX FORTE Square Pharmaceuticals Ltd. Cefpodoxime 80mg/5 ml Powder for Suspension 50 ml: 176.19 MRP
VANPROX P-DROP Square Pharmaceuticals Ltd. Cefpodoxime 20mg/ml Paediatric Drops 15 ml: 60.40 MRP
VANPROX PFS Square Pharmaceuticals Ltd. Cefpodoxime 40mg/5 ml Powder for Suspension 50 ml: 98.65 MRP
VERCEF 100ML Beximco Pharmaceuticals Ltd Cefpodoxime Proxetil USP eq. to Cefpodoxime 40mg/5ml Suspension 100ml: 195.00 MRP
VERCEF 50ML Beximco Pharmaceuticals Ltd Cefpodoxime Proxetil USP eq. to Cefpodoxime 40mg/5ml Suspension 50ml: 98.00 MRP
VERCEF DROP Beximco Pharmaceuticals Ltd Cefpodoxime Proxetil USP eq. to Cefpodoxime 20mg/ml Drop 15ml: 60.00 MRP
VERCEF DS SUSPENSION Beximco Pharmaceuticals Ltd Cefpodoxime Proxetil USP eq. to Cefpodoxime 80mg/5ml Suspension 50ml: 175.00 MRP
VICTORIN Novo Healthcare and Pharma Ltd. Cefpodoxime proxetil INN 20mg/ml Drop 15ml: 60.00 MRP
VICTORIN Capsule Novo Healthcare and Pharma Ltd. Cefpodoxime proxetil INN 200mg Capsule 8's: 320.00 MRP
VICTORIN Suspension Novo Healthcare and Pharma Ltd. Cefpodoxime proxetil INN 40mg/5ml Suspension 50ml: 98.00 MRP
XEPODOX Rangs Pharmaceuticals Ltd. Cefpodoxime proxetil INN 20mg/ml Drop 15ml: 60.00 MRP
XEPODOX Suspension Rangs Pharmaceuticals Ltd. Cefpodoxime proxetil INN 40mg/5ml Suspension 50ml: 98.00 MRP
Ximeprox 100 Incepta Pharmaceuticals Limited Cefpodoxime Proxetil USP equivalent to Cefpodoxime 100 mg Tablet 20's:MRP 340 Tk
Ximeprox 100ml Incepta Pharmaceuticals Limited Cefpodoxime Proxetil USP equivalent to Cefpodoxime 40mg/5ml Suspension 100ml:MRP 195 Tk
Ximeprox 200 Incepta Pharmaceuticals Limited Cefpodoxime Proxetil USP equivalent to Cefpodoxime 200mg Tablet 12's:MRP 336 Tk
Ximeprox 50ml Incepta Pharmaceuticals Limited Cefpodoxime Proxetil USP equivalent to Cefpodoxime 40mg/5ml Suspension 50ml:MRP 98 Tk
Ximeprox Drop Incepta Pharmaceuticals Limited Cefpodoxime Proxetil USP equivalent to Cefpodoxime 100mg/5ml Paed. Drop 15ml:MRP 60 Tk
Ximeprox DS Incepta Pharmaceuticals Limited Cefpodoxime Proxetil USP equivalent to Cefpodoxime 80mg/5ml Suspension 50ml:MRP 175 Tk
XIMOCEF Kumudini Pharma Ltd Cefpodoxime proxetil INN 20mg/ml Drop 50ml: 95.00 MRP
XIMOCEF 200 Kumudini Pharma Ltd Cefpodoxime proxetil INN 200mg Capsule 8's: 320.00 MRP
XIMOCEF Suspension Kumudini Pharma Ltd Cefpodoxime proxetil INN 40mg/5ml Suspension 50ml: 95.00 MRP
XPOTIL Cosmic Chemical Industries Limited Cefpodoxime proxetil INN 40mg/5ml Suspension 50ml: 95.00 MRP
ZEDOXIM Globe Pharmaceuticals Ltd Cefpodoxime proxetil INN 40mg/5ml Suspension 50ml: 95.00 MRP

Gen. MedInfo

Why is this medication prescribed?

Cefpodoxime is a cephalosporin antibiotic used to treat certain infections caused by bacteria such as pneumonia; bronchitis; gonorrhea; and ear, skin, throat, and urinary tract infections. Antibiotics will not work for colds, flu, or other viral infections.

This medication is sometimes prescribed for other uses; ask your doctor for more information.

How should this medicine be used?

Cefpodoxime comes as a tablet/capsule and liquid to take by mouth. It is usually taken every 12 hours (twice a day) for 7-14 days. A single dose is given to treat gonorrhea. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take cefpodoxime exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Shake the liquid well before each use to mix the medication evenly.

The tablets should be swallowed whole and taken with a full glass of water.

Continue to take cefpodoxime even if you feel well. Do not stop taking cefpodoxime without talking to your doctor.

What special precautions should I follow?

 

Before taking cefpodoxime, 

  • tell your doctor if you are allergic to cefpodoxime or any other cephalosporin antibiotic such as cefadroxil (Duricef) or cephalexin (Keflex), penicillin, or any other drugs.
  • tell your doctor what prescription and nonprescription medications you are taking, especially other antibiotics, anticoagulants ('blood thinners') such as warfarin (Coumadin), probenecid (Benemid), and vitamins.
  • tell your doctor if you have or have ever had kidney or liver disease, colitis, or stomach problems.
  • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking cefpodoxime, call your doctor.
  • if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking cefpodoxime.

What special dietary instructions should I follow? 

Take cefpodoxime tablets with food. The liquid may be taken with or without food.

What should I do if I forget a dose? 

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

What side effects can this medication cause? 

Cefpodoxime may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • upset stomach

  • diarrhea

  • vomiting

  • mild skin rash

If you experience any of the following symptoms, call your doctor immediately:

  • severe skin rash

  • itching

  • hives

  • difficulty breathing or swallowing

  • wheezing

  • unusual bleeding or bruising

  • sore throat

  • painful mouth or throat sores

  • vaginal infection

What should I know about storage and disposal of this medication? 

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store the tablets at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Keep liquid medicine in the refrigerator, tightly closed, and throw away any unused medication after 14 days. Do not freeze.

This medication may cause other side effects.  Consult your doctor if you have any unusual problems while taking this.

In case of emergency/overdose

In case of overdose, consult your doctor. If the victim has collapsed or is not breathing, consult local medical emergency services.

What other information should I know?

Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your response to this medicine.

Do not let anyone else use your medication. If you still have symptoms and need further treatment, consult your doctor.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Ref:  U.S. National Library of Medicine.


This information is provided for reference only and not a replacement for and should only be used in conjunction with full consultation with a registered medical practitioner. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, mph-bd shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise.

Simple Breath Test Might Diagnose Heart Failure An experimental breath test, designed to quickly identify patients suffering from heart failure simply by analyzing the contents of a...
Osteoporosis drug stops Breast cancer growth   News & Events News & Events     HIGHLIGHTS Osteoporosis drug stops growth of breast cancer...
Generic drug safety info loophole FDA plans to close generic drug safety info loophole The US Food and Drug Administration has announced plans to speed up the dissemination of...
Large trials unpublished   News & Events News & Events   HIGHLIGHTS Almost 1 in 3 of large clinical trials unpublished after...
TB activists boo Indian minister News & Events News & Events   HIGHLIGHTS TB activists at world conference boo Indian minister off...
Key bone marrow protein identified News & Events News & Events   HIGHLIGHTS Key bone marrow protein identified as potential new leukemia...