(sef' a klor)
P : Caution when used during pregnancy
L : Caution when used during lactation
|| See TERMINOLOGY & ABBREVIATIONS ||
Indication(s) & Dosage
Urinary tract infections, Upper and lower respiratory tract infections, Skin
infections, Otitis media
May be taken with or without food.
Known hypersensitivity to cephalosporins.
Severe renal impairment; history of allergy to penicillin; pregnancy, lactation.
Allergic reactions; diarrhoea, nausea, vomiting;
candidiasis, eosinophilia; elevated transaminases.
Probenecid slows tubular
Plasma levels slightly reduced.
False-positive results for direct Coombs' test and urine sugar (Benedict's, Fehling's or other reagents but not with enzyme-based methods). Interferes with Jaffe method of measuring creatinine.
Category B: Either animal-reproduction studies have not demonstrated a foetal risk but there are no controlled studies in pregnant women or animal-reproduction studies have shown an adverse effect (other than a decrease in fertility) that was not confirmed in controlled studies in women in the 1sttrimester (and there is no evidence of a risk in later trimesters).
Oral: Store at 15-30Â°C.
Cefaclor binds to one or more of the
penicillin-binding proteins (PBPs) which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell wall, thus inhibiting
biosynthesis and arresting cell wall assembly resulting in bacterial cell death. It has bactericidal activity against gm-ve bacteria including E.
coli, S. pneumoniae, N. gonorrhoea, P. mirabilis and H. influenzae.
J01DC04 - cefaclor
Search Google: Cefaclor
|Brand Name||Manufacturer/Marketer||Composition||Dosage Form||Pack Size & Price|
|ABACLOR||ACI Ltd.||Cefaclor monohydrate 100mg/1ml||Drop||15ml: 125.47 MRP|
|ABACLOR Capsule||ACI Ltd.||Cefaclor monohydrate 250mg & 500mg||Capsule||250mg x20's, 500mg x12's: 421.60 & 481.80 MRP|
|ABACLOR Suspension||ACI Ltd.||Cefaclor monohydrate 125mg/5ml||Suspension||100ml: 200.75 MRP|
|B-CLOR||Benham Pharmaceuticals Ltd||Cefaclor monohydrate USP 500mg||Capsule||12's: 461.16 MRP|
|BIOCEF||Sandoz/Novartis||Cefaclor monohydrate USP 250mg & 500mg||Capsule||250mg x 20's: MRP 500.00; 500mg x 20's: MRP 920.00|
|BIOCEF SUSPENSION||Sandoz/Novartis||Cefaclor Monohydrate USP 131.11mg equivalent to Cefaclor 125mg/5ml||Suspension||100ml: MRP 295.26|
|CEFLON||Eskayef Bangladesh Ltd||Cefaclor Monohydrate USP 250mg & 500mg||Capsule||250mg x16's & 500mg x8's MRP: 256.00 & 240.00|
|CEFLON Drop||Eskayef Bangladesh Ltd||Cefaclor Monohydrate USP 100mg/ml||Drop||15ml MRP: 125.00|
|CEFLON Suspension||Eskayef Bangladesh Ltd||Cefaclor Monohydrate USP 125mg/5ml||Suspension||100ml MRP: 200.00|
|CEFTICLOR||Renata Limited||Cefaclor monohydrate 100mg/1ml||Drop||15ml: 125.47 MRP|
|CEFTICLOR 375 ER||Renata Limited||Cefaclor monohydrate 375mg||Tablet (extended release)||12's: 361.32 MRP|
|CEFTICLOR Capsule||Renata Limited||Cefaclor monohydrate 250mg & 500mg||Capsule||12's each: 252.46 & 457.68 MRP|
|CEFTICLOR Suspension||Renata Limited||Cefaclor monohydrate 125mg/5ml||Suspension||100ml: 190.72 MRP|
|CFL||Sharif Pharmaceuticals Ltd.||Cefaclor monohydrate 100mg/1ml||Drop||15ml: 125.00 MRP|
|CFL Suspension||Sharif Pharmaceuticals Ltd.||Cefaclor monohydrate 125mg/5ml||Suspension||100ml: 190.00 MRP|
|CLOBAC||Opsonin Pharma Limited||Cefaclor monohydrate 100mg/1ml||Drop||15ml: 125.00 MRP|
|CLOBAC Suspension||Opsonin Pharma Limited||Cefaclor monohydrate 125mg/5ml||Suspension||100ml: 180.00 MRP|
|CLOCEF||Amico Laboratories Ltd.||Cefaclor monohydrate 500mg||Capsule||20's: 600.00 MRP|
|CLOCEF Suspension||Amico Laboratories Ltd.||Cefaclor monohydrate 125mg/5ml||Suspension||100ml: 175.00 MRP|
|CLOROCEF||IBN SINA Pharmaceutical Industry Ltd.||Cefaclor monohydrate 100mg/1ml||Drop||15ml: 130.00 IP|
|CLOROCEF Capsule||IBN SINA Pharmaceutical Industry Ltd.||Cefaclor monohydrate 250mg & 500mg||Capsule||12's each: 264.00, 480.00 IP|
|CLOROCEF Suspension||IBN SINA Pharmaceutical Industry Ltd.||Cefaclor monohydrate 125mg/5ml||Suspension||100ml: 205.00 IP|
|LORACEF 500||Square Pharmaceuticals Ltd.||Cefaclor 500mg||Capsule||1x6's: 229.56 MRP|
|LORACEF P-DROP||Square Pharmaceuticals Ltd.||Cefaclor 125mg/1.25 ml||Paediatric Drops||15 ml: 125.85 MRP|
|LORACEF PFS||Square Pharmaceuticals Ltd.||Cefaclor 125mg/5 ml||Powder for Suspension||100 ml: 191.30 MRP|
|NAVACEF||Navana Pharmaceuticals Limited||Cefaclor monohydrate 125mg/1.25ml||Drop||15ml: 125.45 MRP|
|NAVACEF Capsule||Navana Pharmaceuticals Limited||Cefaclor monohydrate 250mg & 500mg||Capsule||250mg x25's, 500mg x24's: 505.68 & 963.60 MRP|
|NAVACEF Suspension||Navana Pharmaceuticals Limited||Cefaclor monohydrate 125mg/5ml||Suspension||60ml, 100ml: 130.48 & 190.70 MRP|
|Oticlor 500||Incepta Pharmaceuticals Limited||Cefaclor Monohydrate USP 524.46 mg equivalent to Cefaclor 500mg||Capsule||2x6's:MRP 480 Tk|
|OTICLOR Paed||Incepta Pharmaceuticals Limited||Cefaclor Monohydrate USP 104.9 mg equivalent to Cefaclor 100mg/ml||Paediatric Drops||15ml: 125.00 MRP|
|Oticlor Suspension||Incepta Pharmaceuticals Limited||Cefaclor Monohydrate USP 131.11 mg equivalent to Cefaclor 125mg/5ml||Suspension||100ml:MRP 180 Tk|
|SEFALOR||Techno Drugs||Cefaclor monohydrate 500mg||Capsule||12's: 360.00 MRP|
|SEFALOR Suspension||Techno Drugs||Cefaclor monohydrate 125mg/5ml||Suspension||100ml: 180.00 MRP|
Why is Cefaclor prescribed?
Cefaclor is used to treat certain infections caused by bacteria, such as pneumonia and infections of the ears, lungs, throat, urinary tract, and skin. Cefaclor is in a class of medications called cephalosporin antibiotics. It works by stopping the growth of bacteria. Antibiotics will not work for colds, flu, or other viral infections.
How should Cefaclor be used?
Cefaclor may come as a capsule, an extended-release tablet and a suspension to take by mouth. The capsule and liquid are usually taken every 8 hours or every 12 hours. The long-acting tablet is usually taken every 12 hours, within 1 hour of eating a meal. To help you remember to take cefaclor, take it around the same time every day. Follow the directions on your prescription label carefully, and ask your Doctor to explain any part you do not understand. Take cefaclor exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
Shake the liquid well before each use to mix the medication evenly.
The capsules and tablets should be swallowed whole and taken with a full glass of water. Swallow the long-acting tablets whole; do not split, chew, or crush them.
Take cefaclor until you finish the prescription, even if you feel better. Stopping cefaclor too soon may cause bacteria to become resistant to antibiotics.
Other uses for Cefaclor
Cefaclor may be prescribed for other uses; ask your Doctor for more information.
What special precautions to follow?
Before taking cefaclor,
- inform your Doctor if you are allergic to cefaclor, penicillin, cefadroxil, cefamandole, cefazolin, cefdinir, cefditoren, cefepime, cefixime, cefmetazole, cefonicid, cefoperazone, cefotaxime, cefoxitin, cefpodoxime, cefprozil, ceftazidime, ceftibuten, ceftizoxime, ceftriaxone, cefuroxime, cephalexin, cephapirin, cephradine, loracarbef, or any other medications.
- inform your Doctor what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking. Be sure to mention either of the following: anticoagulants such as warfarin, and probenecid. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
- inform your doctor if you have or have ever had allergies, kidney disease, colitis, or stomach problems.
- inform your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking cefaclor, consult your doctor.
What special dietary instructions to follow?
Unless your doctor informs you otherwise, continue your normal diet.
What to do if I forget a dose?
Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
What side effects can Cefaclor cause?
Cefaclor may cause side effects. Tell your doctor if this symptom is severe or does not go away:
- severe skin rash
- difficulty breathing or swallowing
- joint pain
- painful sores in the mouth or throat
- vaginal itching and discharge
Some side effects can be serious. The following symptoms are uncommon, but if you experience any of them, consult your doctor immediately:
Cefaclor may cause other side effects. Consult your doctor if you have any unusual problems while taking Cefaclor.
If you experience a serious side effect, you or your doctor may send a report to the Office of Directorate General, Drugs Administration.
What storage conditions are needed for Cefaclor?
Keep Cefaclor in the container it came in, tightly closed, and out of reach of children. Store the capsules and tablets at room temperature and away from excess heat and moisture. Throw away any medication that is outdated or no longer needed. Keep liquid medicine in the refrigerator, tightly closed, and throw away any unused medication after 14 days. Do not freeze. Talk to your Doctor about the proper disposal of your medication.
In case of emergency/overdose
In case of overdose, consult your Doctor. If the victim has collapsed or is not breathing, consult local medical emergency services.
Symptoms of overdose may include:
- upset stomach
- stomach pain
What other information to know?
Keep all appointments with your doctor and the laboratory. Your doctor may order certain lab tests to check your body's response to cefaclor.
If you are diabetic, use Clinistix or TesTape to test your urine for sugar while taking Cefaclor.
Do not let anyone else take your medication. If you still have symptoms of infection after you finish the cefaclor, consult your doctor.
It is important for you to keep a written list of all of the prescription and nonprescription medicines you are taking, as well
as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you
are admitted to a hospital. It is also important information to carry with you in case of emergencies.
Ref: MedlinePlus, U.S. Natl. Library of Medicine