mph Bangladesh


(sef proe' zil)

P  - Caution when used during pregnancy

L  - Caution when used during lactation

Molecule Info

Indication & Dosage

OralSkin and soft tissue infections, Susceptible infections Adult: 500mg/day as a single dose or in 2 divided doses, increased to 500mg bid if necessary. Child: 20mg/kg/day once or twice daily, up to a max dose of 500mg once daily, if necessary, bid forotitis media.


Dosage Recommendation


Half normal dose.

Special Populations: Dose reduction inrenal impairment. CrCl <30 mL/min: 1/2 the standard dose.


May be taken with or without food. May be taken w/ meals to reduce GI discomfort.



Special Precautions

Hypersensitivity to penicillins; renal impairment; porphyria. Monitor renal and haematologic status. Pregnancy, lactation.

Adverse Drug Reactions

Nausea; vomiting; diarrhoea; hypersensitivity reactions; nephrotoxicity; convulsions; CNS toxicity; hepatic dysfunction; haematologic disorders; pain at Inj site (IM); thrombophlebitis (IV infusion); superinfection with prolonged use. Potentially Fatal: Pseudomembranous colitis.

Drug Interactions

Renal excretion delayed by probenecid. Decreases contraceptive effect of oestrogen-containing oral contraceptives.

Lab Interference

Positive direct antiglobulin Coombs' test; falsely high values with Jaffe method of measuring creatinine concentrations; +ve reactions for false glucose using copper-reduction reactions; transient increases in liver enzyme values.

Pregnancy Category

Category B: Either animal-reproduction studies have not demonstrated a foetal risk but there are no controlled studies in pregnant women or animal-reproduction studies have shown an adverse effect  (other than a decrease in fertility) that was not confirmed in controlled studies in women in the 1sttrimester (and there is no evidence of a risk in later trimesters).


Cefprozil inhibits cell wall synthesis and has activity against a broad range of gram-positive and gram-negative bacteria. Absorption: Well absorbed from the GI tract. Bioavailability: 90-95%. Distribution: 35-45% bound to plasma proteins. Widely distributed in the body tissues. Excretion: Plasma half-life: 1-1. 4 hr; prolonged in renal impairment. About 60% excreted unchanged in the urine.

mph Class


ATC Classification

J01DC10 - cefprozil;


Brand/Product Info

Total Products : 2  
Brand Name Manufacturer/Marketer Composition Dosage Form Pack Size & Price
CEFOZIL Popular Pharmaceuticals Ltd. Cefprozil 250mg & 500mg Tablet 250mg x10's, 500mg x8's: 301.10 & 441.48 MRP
CEFOZIL Suspension Popular Pharmaceuticals Ltd. Cefprozil 125mg/5ml Suspension 50ml: 230.87 MRP

Gen. MedInfo

Why is this medication prescribed?

Cefprozil is used to treat certain infections caused by bacteria, such as bronchitis and infections of the ears, throat, sinuses, and skin. Cefprozil is in a class of medications called cephalosporin antibiotics. It works by stopping the growth of bacteria. Antibiotics will not work for colds, flu, or other viral infections.

How should this medicine be used?

Cefprozil may come as a tablet and a suspension (liquid) to take by mouth. It is usually taken every 24 hours (once a day) or every 12 hours (twice a day) for 10 days. To help you remember to take cefprozil, take it around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take cefprozil exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Shake the liquid well before each use to mix the medication evenly.The tablets should be swallowed whole and taken with a full glass of water. Take cefprozil until you finish the prescription, even if you feel better. Stopping cefprozil too soon may cause bacteria to become resistant to antibiotics.

Other uses for this medicine

This medication may be prescribed for other uses; ask your doctor for more information.

What special precautions should I follow?

Before taking cefprozil,

  • tell your doctor if you are allergic to cefprozil, penicillin, cefaclor, cefadroxil, cefamandole, cefazolin, cefdinir, cefditoren, cefepime, cefixime, cefmetazole, cefonicid, cefoperazone, cefotaxime, cefoxitin, cefpodoxime, ceftazidime, ceftibuten, ceftizoxime, ceftriaxone, cefuroxime, cephalexin, cephapirin, cephradine, loracarbef, or any other medications.
  • tell your doctor what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking. Be sure to mention any of the following: anticoagulants  such as warfarin, diuretics, other antibiotics, and probenecid . Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
  • tell your doctor if you have or have ever had kidney disease, phenylketonuria, colitis, or stomach problems.
  • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking cefprozil, consult your doctor.

What special dietary instructions should I follow?

Unless your doctor tells you otherwise, continue your normal diet.

What should I do if I forget a dose?

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

What side effects can this medication cause?

Cefprozil may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • upset stomach
  • diarrhea
  • vomiting
  • stomach pain
  • dizziness

Some side effects can be serious. The following symptoms are uncommon, but if you experience any of them, consult your doctor immediately:

  • severe skin rash
  • itching
  • hives
  • difficulty breathing or swallowing
  • wheezing
  • yellowing of the skin and eyes
  • painful sores in the mouth or throat
  • vaginal discharge and itching
  • diaper rash

Cefprozil may cause other side effects. Consult your doctor if you have any unusual problems while taking this medication. 

What other information should I know?

Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your response to this medicine.

Do not let anyone else use your medication. If you still have symptoms and need further treatment, consult your doctor.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.


This information is provided for reference only and not a replacement for and should only be used in conjunction with full consultation with a registered medical practitioner. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, mph-bd shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise.

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