Oxiconazole

(ox i kon' a zole)

P  - Caution when used during pregnancy

L  - Caution when used during lactation

Molecule Info

 
Indication & Dosage Vaginal
Vaginal candidiasis
Adult: 600 mg pessary as a single dose.
Topical/Cutaneous
Tinea corporis
Adult: Apply 1% cream or lotion once or bid. Duration of treatment: 2 wk fortinea corporis and tinea cruris or 1 mth for tinea pedis.
Elderly: Apply 1% cream or lotion once or bid. Duration of treatment: 2 wk for tinea corporis and tinea cruris or 1 mth for tinea pedis.
Topical/Cutaneous
Tinea cruris
Adult: Apply 1% cream or lotion once or bid. Duration of treatment: 2 wk for tinea corporis and tinea cruris or 1 mth for tinea pedis.
Elderly: Apply 1% cream or lotion once or bid. Duration of treatment: 2 wk for tinea corporis and tinea cruris or 1 mth for tinea pedis.
Topical/Cutaneous
Tinea pedis
Adult: Apply 1% cream or lotion once or bid. Duration of treatment: 2 wk for tinea corporis and tinea cruris or 1 mth for tinea pedis.
Elderly: Apply 1% cream or lotion once or bid. Duration of treatment: 2 wk for tinea corporis and tinea cruris or 1 mth for tinea pedis.
Topical/Cutaneous
Pityriasis versicolor
Adult: Apply 1% cream once daily for 2 wk.
Elderly: Apply 1% cream once daily for 2 wk.
Contraindications Hypersensitivity.
Special Precautions Pregnancy and lactation. Avoid contact with eyes. Intravaginal preparation may damage latex contraceptives. Discontinue if irritation or sensitisation occurs. Cross-sensitisation with other imidazole derivatives may occur.
Adverse Drug Reactions Pruritus, burning, irritation, stinging, erythema, rash, folliculitis, nodules, pain, papules, maceration, fissuring, contact dermatitis, dyshidrotic eczema, tingling.
Pregnancy Category (US FDA) Category B: Either animal-reproduction studies have not demonstrated a foetal risk but there are no controlled studies in pregnant women or animal-reproduction studies have shown an adverse effect (other than a decrease in fertility) that was not confirmed in controlled studies in women in the 1sttrimester (and there is no evidence of a risk in later trimesters).
Storage Topical/Cutaneous: Store at 15-30°C (59-86°F).
Pharmacology Oxiconazole, a synthetic azole antifungal, is usually fungistatic but may be fungicidal in high concentrations. It exerts its antifungal activity by interfering with ergosterol synthesis and altering cellular membranes. It also has some antibacterial activity against aerobic gram-positive organisms.
Absorption: Absorbed in each dermis layer.
Distribution: To each dermis layer.
Excretion: Via urine (<0.3%).
ATC Classification D01AC11 - oxiconazole; Belongs to the class of imidazole and triazole derivatives for topical use. Used in the treatment of fungal infection. 
G01AF17 - oxiconazole; Belongs to the class of imidazole derivative antiinfectives. Used in the treatment of gynecological infections.

Return to top

Brand/Product Info


Total Products : 1 
Brand Name Manufacturer/Marketer Composition Dosage Form Pack Size & Price
OXIFUN CRM Square Pharmaceuticals Ltd. Oxiconazole 0.01 Cream 10 gm: 50.35 MRP

Gen. MedInfo

Why is this medication prescribed? 

Oxiconazole, an antifungal agent, is used to treat skin infections such as athlete's foot, jock itch, and ringworm.

This medication is sometimes prescribed for other uses; ask your doctor for more information.

How should this medicine be used?

Oxiconazole comes in a cream or lotion to be applied to your skin. Oxiconazole usually is applied once a day (in the evening) or twice a day (in the morning and evening). Follow the directions on your prescription label carefully, and ask your doctor to explain any part you do not understand. Use oxiconazole exactly as directed. Do not use more or less of it or use it more often than prescribed by your doctor.

Thoroughly clean the infected area, allow it to dry, and then gently rub the medication in until most of it disappears. Use just enough medication to cover the affected area. You should wash your hands after applying the medication.

What special precautions should I follow?

Before using oxiconazole,

  • tell your doctor if you are allergic to oxiconazole or any other drugs.
  • tell your doctor what prescription and nonprescription drugs you are taking, including vitamins.
  • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while using oxiconazole, call your doctor.

What should I do if I forget a dose?

Apply the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not apply a double dose to make up for a missed one.

What side effects can this medication cause?

Oxiconazole may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • itching

  • burning

  • redness

  • dry or flaky skin

  • tingling

If you experience any of the following symptoms, call your doctor immediately:

  • pain

  • swelling

  • open sores

  • skin rash

What other information should I know?

Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your response to this medicine.

Do not let anyone else use your medication. If you still have symptoms and need further treatment, consult your doctor.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Ref:  U.S. National Library of Medicine.


This information is provided for reference only and not a replacement for and should only be used in conjunction with full consultation with a registered medical practitioner. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, mph-bd shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise.