PCaution when used during lactation - Caution when used during pregnancy

Molecule Info

 
Indication(s) & Dosage

Oral route
Constipation
Adult: 5-10 mg at night.
Child: >4 yr: 5 mg at night time. 
Elderly: 

Bowel evacuation
Adult: Initially, 10-20 mg the night before the procedure followed by 10 mg suppository admin rectally the next morning.
Child: >10 yr: Same as adult dose. 4-10 yr: 5 mg the night before the procedure and 5 mg suppository admin rectally the following morning.

Rectal route
Constipation
Adult: 10 mg suppository/enema admin in the morning.
Child: <10 yr: 5 mg in the morning.

Administration May be taken with or without food. May be taken w/ meals to reduce GI discomfort.
Overdosage Overdosage may result in diarrhoea with excessive loss of water and electrolytes.
Contraindications Acute surgical abdomen or intestinal obstruction, severe dehydration, faecal impaction, chronic use.
Special Precautions Swallow the tab whole. Pregnancy; inflammatory bowel disease.
Adverse Drug Reaction(s) Abdominal discomfort (colic, cramps). Suppositories may cause irritation and proctitis.
Drug Interactions Do not give antacids or milk within 1 hr of taking the drug (enteric coated).
Lab Interference False urinary glucose levels.
Pregnancy Category (FDA) Category C: Either studies in animals have revealed adverse effects on the foetus (teratogenic or embryocidal or other) and there are no controlled studies in women or studies in women and animals are not available. Drugs should be given only if the potential benefit justifies the potential risk to the foetus.
Storage Oral: Store below 25°C. Rectal: Store below 25°C.
Pharmacology Bisacodyl acts mainly in the large intestine by increasng its motility to effect bowel evacuation.
Onset: 6-12 hr (oral). 15-60 min (rectal).
Absorption: Minimal from the GI tract (oral, as enteric-coated tablets/suppositories).
Metabolism: Converted to bis(p-hydroxyphenyl)pyridyl-2-methane by intestinal or bacterial enzymes.
Excretion: Faeces; urine (as glucuronide).
ATC Classification A06AB02 - bisacodyl; Belongs to the class of contact laxatives. 
A06AG02 - bisacodyl; Belongs to the class of enemas. Used in the treatment of constipation.

 

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Brand/Product Info


Total Products : 1 
Brand Name Manufacturer/Marketer Composition Dosage Form Pack Size & Price
DURALAX Opsonin Pharma Limited Bisacodyl 5mg Tablet 200's: 140.00 MRP