(ok'' see met az' oh leen)
P Â - Caution when used during pregnancy
L Â - Caution when used during lactation
|Indication & Dosage||Nasal
Adult:Â As 0.05% solution: Spray 1-3 times into each nostril bid.
Child:Â â‰¥6 yr: Instill or spray 0.05% solution 1-3 times into each nostril bid.
Adult:Â Instil 1-2 drops of 0.025% solution into the eye(s) 6 hrly when necessary.
Child:Â â‰¥6 yr: Instill 1-2 drops of 0.025% solution into the eye(s) 6 hrly when necessary.
|Administration||Should be taken with food. Take immediately after
|Contraindications||Glaucoma; hyperthyroidism, heart disease (including angina), hypertension, advanced arteriosclerotic conditions. Children <6 yr.|
|Special Precautions||Pregnancy, lactation. Difficulty in urination secondary to prostate enlargement; DM.|
|Adverse Drug Reactions||Nasal drops or spray: Local stinging or burning, sneezing, dryness of mouth and throat. Prolonged or frequent use may cause rebound congestion. Headache, insomnia, tachycardia, hypertension, nervousness, nausea, dizziness, palpitation, arrhythmia. Eye drops: Dryness of eye.|
|Drug Interactions||Potentially Fatal:Â Hypertensive crisis with MAOIs.Â Please consult detailed drug interactions before prescribing.|
|Pregnancy Category (US FDA)||Category C: Either studies in animals have revealed adverse effects on the foetus (teratogenic or embryocidal or other) and there are no controlled studies in women or studies in women and animals are not available. Drugs should be given only if the potential benefit justifies the potential risk to the foetus.|
|Pharmacology||Oxymetazoline is a direct-acting sympathomimetic
which has vasoconstrictor effect on mucosal blood vessels when applied topically and in turn reduces oedema of the nasal mucosa.
Duration:Â Up to 12 hr.
|ATC Classification||S01GA04 - oxymetazoline; Belongs to the class of
sympathomimetics used as ophthalmologic decongestants.Â
R01AA05 - oxymetazoline; Belongs to the class of topical sympathomimetic agents used as nasal decongestants.Â
R01AB07 - oxymetazoline; Belongs to the class of topical sympathomimetic combination preparations, excluding corticosteroids. Used as nasal decongestants.
|Brand Name||Manufacturer/Marketer||Composition||Dosage Form||Pack Size & Price|
|AFRIN 0.025%||Aristopharma Ltd.||Oxymetazoline hydrochloride 0.025%||Drop||10ml: 40.00 MRP|
|AFRIN 0.05%||Aristopharma Ltd.||Oxymetazoline hydrochloride 0.05%||Drop||10ml: 45.00 MRP|
|AZOLIN 0.025%||The Acme Laboratories Ltd.||Oxymetazoline hydrochloride 0.025%||Drop||10ml: 40.00 MRP|
|AZOLIN 0.05%||The Acme Laboratories Ltd.||Oxymetazoline hydrochloride 0.05%||Drop||10ml: 45.00 MRP|
|G-CON 0.025%||Kemiko Pharmaceuticals Ltd||Oxymetazoline hydrochloride 0.025%||Drop||10ml: 40.00 MRP|
|G-CON 0.05%||Kemiko Pharmaceuticals Ltd||Oxymetazoline hydrochloride 0.05%||Drop||10ml: 45.00 MRP|
|NAZOLIN Spray||Beximco Pharmaceuticals Ltd||Oxymetazoline Hydrochloride USP 0.05%||Nasal Spray||200MD: 130.00 MRP|
|NOCON 0.025%||Square Pharmaceuticals Ltd.||Oxymetazoline HCl USP 0.25mg/ml||Nasal Drop||6's: 180.66 MRP|
|Rynex 0.025%||Incepta Pharmaceuticals Limited||Oxymetazoline Hydrochloride 0.025%||Nasal Drop||10ml:MRP 40 Tk|
|Rynex 0.05%||Incepta Pharmaceuticals Limited||Oxymetazoline Hydrochloride 0.05%||Nasal Drop||10ml:MRP 45 Tk|
|Rynex Spray||Incepta Pharmaceuticals Limited||Oxymetazoline Hydrochloride BP 25mcg per actuation||Nasal Spray||200 Metered Dose:MRP 80 Tk|
|XYLOCON 0.025%||Square Pharmaceuticals Ltd.||Oxymetazoline 0.025%||Nasal Drops||6's: 240.78|
|XYLOCON 0.05%||Square Pharmaceuticals Ltd.||Oxymetazoline 0.05%||Nasal Drops||6's: 270.78|
Why is this medication prescribed?
Oxymetazoline nasal spray is used to relieve nasal discomfort caused by colds, allergies, and hay fever. It is also used to relieve sinus congestion and pressure. Oxymetazoline nasal spray should not be used to treat children younger than 6 years of age unless it is recommended by a doctor. Children 6 to 12 years of age should use oxymetazoline nasal spray carefully and under adult supervision. Oxymetazoline is in a class of medications called nasal decongestants. It works by narrowing the blood vessels in the nasal passages.
How should this medicine be used?
Oxymetazoline comes as a solution (liquid) to spray into the nose. It is usually used every 10 to 12 hours as needed, but not more often than twice in a 24-hour period. Follow the directions on the package label or on your prescription label carefully, and ask your doctor to explain any part you do not understand. Use oxymetazoline nasal spray exactly as directed. Do not use more or less of it or use it more often than prescribed by your doctor or directed on the label.
If you use oxymetazoline nasal spray for more often or for longer than the recommended period of time, your congestion may get worse or may improve but come back. Do not use oxymetazoline nasal spray for longer than 3 days. If your symptoms do not get better after 3 days of treatment, stop using oxymetazoline and call your doctor.
Oxymetazoline nasal spray is only for use in the nose. Do not swallow the medication.
To prevent the spread of infection, do not share your spray dispenser with anyone else. Rinse the tip of the dispenser with hot water or wipe it clean after you use it.
Follow the directions for using the nasal spray that appear on the package label. If you are using a product that comes in a pump dispenser, press down on the rim several times before using your first dose to prime the pump, according to the directions on the label. When you are ready to use the spray, hold your head upright without tilting and place the tip of the bottle in your nostril. For the nasal spray, squeeze the bottle quickly and firmly. For products that come in a pump dispenser, press down on the rim with a firm, even stroke and breathe in deeply.
Other uses for this medicineReturn to top
This medication may be prescribed for other uses. Ask your doctor for more information.
What special precautions should I follow?Return to top
Before using oxymetazoline,
- tell your doctor if you are allergic to oxymetazoline, or any other medications.
- tell your doctor what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to tell your doctorif you are taking the following medications or have stopped taking them within the past two weeks: isocarboxazid, phenelzine, selegiline and tranylcypromine.
- tell your doctor if you have or have ever had high blood pressure, diabetes, difficulty urinating due to an enlarged prostate gland, or thyroid or heart disease.
- tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while using oxymetazoline nasal spray, call your doctor.
What special dietary instructions should I follow?Return to top
Unless your doctor tells you otherwise, continue your normal diet.
What should I do if I forget a dose?Return to top
This medication is usually used as needed. If your doctor has told you to use oxymetazoline regularly, use the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not use a double dose to make up for a missed one.
What side effects can this medication cause?Return to topÂ
Oxymetazoline may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
increased nasal discharge
dryness inside the nose
difficulty falling asleep or staying asleep
Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately:
Oxymetazoline nasal spray may cause other side effects. Call your doctor if you have any unusual problems while using this medication.
What should I know about storage and disposal of this medication?Return to top
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat, light, and moisture (not in the bathroom). Do not freeze the medication. Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.
In case of emergency/overdose
In case of overdose,Â consult your doctor. If the victim has collapsed or is not breathing, consult local medical emergency services.
What other information should I know?
Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your response to this medicine.
Do not let anyone else use your medication. If you still have symptoms and need further treatment, consult your doctor.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
Ref:Â Â U.S. National Library of Medicine.
This information is provided for reference only and not a replacement for and should only be used in conjunction with full consultation with a registered medical practitioner. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, mph-bd shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise.