mph Bangladesh


(in dap' a mide)

PCaution when used during lactation : Caution when used during pregnancy

LCaution when used during lactation : Caution when used during lactation

Molecule Info

Indication(s) & Dosage

Essential hypertension.

Adult: 1.25-2.5 mg Sustained Release (SR) formulation orally once daily, alone or in conjunction with other antihypertensives.

Adult: 2.5 mg (SR formulation) orally once daily increased to 5 mg daily after 1 wk if needed.

Administration Should be taken with food.
Overdosage Nausea, vomiting, weakness, GI disorders, electrolyte imbalance. In severe cases, hypotension and respiratory depression. Stomach emptying recommended.
Contraindications Anuria, severe hepatic impairment.
Special Precautions Pregnancy, lactation, elderly, renal impairment, fluid or electrolyte imbalance, hyperuricaemia, DM, lupus erythematosus.
Adverse Drug Reaction(s) Headache, dizziness, weakness, drowsiness, fatigue, agitation, nervousness, anorexia, nausea, vomiting, pain, diarrhoea, constipation, orthostatic hypotension, palpitations, hypokalaemia, hyponatraemia, metabolic alkalosis.
Drug Interactions Additive effect with other antihypertensive agents and diuretics. Increased chance of hypokalaemia with corticosteroids, corticotropin and amphotericin.
Potentially Fatal: Increased risk of lithium toxicity. Hypokalaemia enhances digitalis toxicity with cardiac gycosides. Please consult detailed drug interactions before prescribing.
Pregnancy Category (FDA) 

Category B: Either animal-reproduction studies have not demonstrated a foetal risk but there are no controlled studies in pregnant women or animal-reproduction studies have shown an adverse effect (other than a decrease in fertility) that was not confirmed in controlled studies in women in the 1sttrimester (and there is no evidence of a risk in later trimesters).

Category D: If used in gestational HTN. There is positive evidence of human foetal risk, but the benefits from use in pregnant women may be acceptable despite the risk (e.g., if the drug is needed in a life-threatening situation or for a serious disease for which safer drugs cannot be used or are ineffective).

Storage Oral: Store at 20-25°C.
Pharmacology Indapamide enhances excretion of sodium, chloride and water by interfering with the transport of sodium ions across the renal tubular epithelium.
Absorption: Rapidly and completely absorbed from the GI tract (oral). Peak plasma levels are achieved within 2-2.5 hr.
Distribution: Widely distributed, preferentially and reversibly bound to erythrocytes.
Metabolism: Extensively metabolised in the liver.
Excretion: Via urine (60-70% as metabolites, 5-7% as unchanged), via faeces (16-23% remaining dose); 14 hr (elimination half-life).
ATC Classification C03BA11 - indapamide; Belongs to the class of low-ceiling sulfonamide diuretics. Used to promote excretion of urine.


Brand/Product Info

Total Products : 12            
Brand Name Manufacturer/Marketer Composition Dosage Form Pack Size & Price
DIHERT SR Sandoz/Novartis Indapamide BP 1.5mg Tablet 2x14's, MRP 224.00
HYPEN Opsonin Pharma Limited Indapamide BP 1.5mg Tablet (sustained release) 30's: 150.00 MRP
HYPEN SR Opsonin Pharma Limited Indapamide BP 1.5mg Tablet (sustained release) 30's: 150.00 MRP
Idatix 1.5 Incepta Pharmaceuticals Limited Indapamide BP 1.5 mg SR Tablet 10x5's :MRP 250 Tk
INDAPA-SR Drug International Ltd Indapamide BP 1.5mg Tablet (sustained release) 50's: 250.00 MRP
INDIMIDE SR Healthcare Pharmacuticals Ltd. Indapamide BP 1.5 mg SR Tablet 30's MRP 195 Tk
IPIDE-SR Renata Limited Indapamide BP 1.5mg Tablet (sustained release) 30's: 150.00 MRP
NATRI-SR Renata Limited Indapamide BP 1.5mg Tablet (sustained release) 30's: 150.00 MRP
NATRILIX SR Servier Bangladesh Operation Indapamide BP 1.5mg sustained release tablet Tablet 30's: 265.80 IP
REPRES Square Pharmaceuticals Ltd. Indapamide 1.5mg Tablet 3x10's: 150.90 MRP
TRILIX SR Silva Pharmaceuticals Limited Indapamide BP 1.5mg Tablet (sustained release) 20's: 100.38 MRP
XELIX SR Aristopharma Ltd. Indapamide BP 1.5mg Tablet (sustained release) 30's: 150.00 MRP

Gen. MedInfo

Why is this medication prescribed?


Indapamide, a 'water pill,' is used to reduce the swelling and fluid retention caused by heart disease. It also is used to treat high blood pressure. It causes the kidneys to get rid of unneeded water and salt from the body into the urine.


This medicine is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

How should this medicine be used?


Indapamide comes as a tablet to take by mouth. It usually is taken once a day, in the morning. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take indapamide exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.


Indapamide controls high blood pressure but does not cure it. Continue to take indapamide even if you feel well. Do not stop taking indapamide without talking to your doctor.

Other uses for this medicine



Indapamide also is used to treat swelling and fluid retention caused by various medical conditions other than heart disease. Talk to your doctor about the possible risks of using this medicine for your condition.

What special precautions should I follow?

Before taking indapamide,


  • tell your doctor if you are allergic to indapamide, sulfa drugs, or any other drugs.
  • tell your doctor what prescription and nonprescription medications you are taking, especially other medications for high blood pressure, corticosteroids (e.g., prednisone), digoxin, indomethacin, lithium, probenecid and vitamins.
  • tell your doctor if you have or have ever had heart rhythm problems, diabetes, gout, or kidney, liver, thyroid, or parathyroid disease.
  • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. Do not breast-feed while taking this medicine. If you become pregnant while taking indapamide, call your doctor.
  • if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking indapamide.
  • you should know that this drug may make you drowsy. Do not drive a car or operate machinery until you know how this drug affects you.
  • remember that alcohol can add to the drowsiness caused by this drug.

What special dietary instructions should I follow?



Follow your doctor's directions. They may include a daily exercise program and a low-sodium or low-salt diet, potassium supplements, and increased amounts of potassium-rich foods (e.g., bananas, prunes, raisins, and orange juice) in your diet.

What should I do if I forget a dose?



Take the missed dose as soon as you remember it. However, if it is almost time for your next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

What side effects can this medication cause?

Frequent urination may last for up to 6 hours after a dose and should decrease after you take indapamide for a few weeks. Tell your doctor if any of these symptoms are severe or do not go away:


  • muscle cramps

  • drowsiness

  • dizziness

  • confusion

  • thirst

  • upset stomach

  • vomiting

  • stomach cramps

  • decreased sexual ability

  • blurred vision

If you have any of the following symptoms, call your doctor immediately:


  • rapid, excessive weight loss

  • severe skin rash with itching

  • difficulty breathing or swallowing

What should I know about storage and disposal of this medication?



Keep this medicine in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medicine that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medicine.

In case of emergency/overdose

In case of overdose, consult your doctor. If the victim has collapsed or is not breathing, consult local medical emergency services.

What other information should I know?

Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your response to this medicine.

Do not let anyone else use your medication. If you still have symptoms and need further treatment, consult your doctor.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Ref:  U.S. National Library of Medicine.

This information is provided for reference only and not a replacement for and should only be used in conjunction with full consultation with a registered medical practitioner. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, mph-bd shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise.

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